Cognitive Flexibility Training for Persistent Pain: Neuroimaging Pilot (COFLEX-i)
CompletedNot applicableNCT03720821
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
To determine whether a 5-week computer-based cognitive training intervention results in changes in resting-state functional connectivity (rsFC) within the brain networks.
Study details
- Official title
- Cognitive Flexibility Training for Persistent Pain: Neuroimaging Pilot (COFLEX-i)
- Interventions
- Behavioral: Cognitive Training + fMRI
- Sponsor
- Washington University School of Medicine
- Start date
- 2019-07-16
- Primary completion
- 2021-06-30
- Sex
- All
- Age range
- from 18 Years to 70 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Adults between 18 to 70 years old with chronic hip, knee or back pain for \>3 months * Documented moderate to severe chronic pain * English fluency * Access to a computer at home and an email account Exclusion Criteria: * Lack of email/lack of basic computer skills * Diagnosed Alzheimer's or documented severe cognitive impairment * Severely impaired vision or color blindness * Unable to complete cognitive testing * An interventional pain procedure within one week prior to enrollment testing * Scheduled to undergo a pain procedure during the five weeks of cognitive training * Self-reported claustrophobia * Contraindication to an MRI scan (i.e. presence of metallic foreign body such as an artificial joint or aneurism clip, implanted pacemaker or spinal cord stimulator)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03720821