Effect of Cognitive Behavioral Therapy on Chronic Low Back Pain With Sensitization
CompletedNot applicableNCT03863808
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
PURPOSE: The main objectives of the study are: 1. To find the efficacy of using cognitive behavioural therapy on chronic low back pain with central sensitization. 2. To assist in planning an ideal physical therapy rehabilitation program for these patients. BACKGROUND: Recent research has shown that CLBP is a multifactorial disorder comprising psychosocial factors like pain catastrophization, fear avoidance and central sensitization. Central sensitization has been defined as "An amplification of neural signaling within the central nervous system that elicits pain hypersensitivity", and "increased responsiveness of nociceptive neurons in the central nervous system to their normal or subthreshold afferent input". Maladaptive behavior, false beliefs and misinformation regarding the cause of the pain are all contributing factors to the chronicity of LBP. Central sensitization has been attributed to cortical reorganization and amplification of the somatosensory representation of the back causing increased pain and further contributing to the maladaptive behavior and beliefs. Cognitive behavioral treatment has been an important intervention for psychological disorders for decades and recently has gained a lot of interest as an intervention for chronic pain in general and CLBP in specific. HYPOTHESES: It will be hypothesized that: Cognitive behavioural therapy will have a significant effect on centrally sensitized pain intensity and disability. RESEARCH QUESTION:" Does cognitive behavioral therapy have a significant effect on chronic low back pain with central sensitization"
Study details
- Official title
- Effect of Cognitive Behavioral Therapy on Chronic Low Back Pain With Sensitization
- Interventions
- Behavioral: Cognitive Behavioural Therapy
- Other: Strengthening exercises
- Sponsor
- Marwa Elsayed
- Collaborators
- MTI University
- Organization
- MTI University
- Start date
- 2017-11-02
- Primary completion
- 2019-08-15
- Sex
- All
- Age range
- from 18 Years to 50 Years
- Results posted
- No results posted in this snapshot
- Countries
- Egypt
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Age between 18- 50. 2. Patient must have experienced low back pain for at least 3 months. 3. Patient must have a score above or equal 40 in the Central Sensitization Inventory (CSI) (Neblett R. C., 2013) (Neblett R, 2015) (Neblett H. M., 2016) (R. De Pauw, 2015) (Mayer TG N. R., 2012) . 4. Patient must have a score of 3 and above on the Numerical Pain Rating Scale. Exclusion Criteria: * Patients were excluded if they had taken pain medications on the day of the assessment. * Patient who had serious spinal pathologies, such as fractures, tumors or inflammatory diseases, such as ankylosing spondylitis, narrowing of spinal canal and other conditions or severe cardiorespiratory diseases. * Uncontrolled mental health condition that prevents successful compliance.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03863808