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Central Sensitisation: clinical trials and information

"Central Sensitisation" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 27 chronic pain registry records worldwide.
1
Trials with Canadian sites
0
Recruiting in Canada
27
Registry records worldwide

Central Sensitisation clinical trials in Canada

1 trial, recruiting first
PhaseProvinces
Brain MRI for Knee OA
NCT05986513
Unknown statusNot applicableOntarioToronto Rehabilitation Institute2023-09-01

Central Sensitisation clinical trials worldwide (outside Canada)

26 trials, 4 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Comparison of Pain, Sensitisation, Function and Quality of Life According to Stenosis Degree in Chronic Neck Pain
NCT06967415
Not yet recruitingNot applicableTurkey (Türkiye)Izmir Democracy University2025-12-15
The Effect of Griffonia Simplicifolia on Pain Intensity, Central and Peripheral Sensitization, Painmodulation in Healthy Volunteers
NCT06893822
RecruitingNot applicableAustriaMedical University of Graz2025-09-12
Effect of Boswellia Serrata on Pain Intensity, Central and Peripheral Sensitization, and Pain Modulation in Healthy Volunteers
NCT07109843
RecruitingNot applicableAustriaMedical University of Graz2025-09-01
Evaluation of Central Sensitization, Fear-Avoidance, and Pain-Pressure Threshold With Chronic Pain After Hysterectomy
NCT04014829
RecruitingSingaporeKK Women's and Children's Hospital2019-07-23
Investigating the Association Between Central Sensitization and Breathing Pattern Disorders
NCT06485414
Unknown statusSouth KoreaSahmyook University2024-07-03
Clinical Trial on Deprescribing Associated With a Psychoeducational Program Using Virtual Reality for Patients With Chronic Pain and Central Sensitization
NCT06964360
CompletedNot applicableSpainBadalona Serveis Assistencials2024-05-06
Pain Phenotypes in Patients With Fibromyalgia Syndrome
NCT05941780
CompletedTurkey (Türkiye)Kutahya Health Sciences University2023-07-10
Nociplastic Pain Symptoms and Sensory Profiles in Low Back Pain
NCT05592405
Active, not recruitingNetherlandsVrije Universiteit Brussel2023-06-01
Effectiveness of Therapeutic Exercise on the Gut Microbiome in Chronic Widespread Pain Patients.
NCT05932433
CompletedNot applicableSpainUniversidad Rey Juan Carlos2023-05-01
Risk of Failed Epidural in Patients With and Without Chronic Pain and Opioid Use
NCT05662566
CompletedDenmarkEske Kvanner Aasvang2023-03-17
Sensorial Discrimination in Chronic Low Back Pain
NCT05169918
CompletedNot applicableTurkey (Türkiye)Istanbul University - Cerrahpasa2022-11-15
What Concept of Manual Therapy is More Effective?
NCT05559021
CompletedNot applicableSpainUniversidad Europea de Madrid2022-10-20
The Segmental Distribution of Hypersensitivity in Patients With Chronic Subacromial Pain Syndrome
NCT06139120
CompletedTurkey (Türkiye)Cukurova University2022-09-20
Childhood Adversity, Inflammatory Reactivity and Persistent Pain
NCT06127693
CompletedSouth AfricaUniversity of Cape Town2022-06-21
Fibromyalgia Syndrome on Patients With Chronic Migraine
NCT05381012
CompletedNot applicableTurkey (Türkiye)Istanbul University - Cerrahpasa2022-05-01
Presence of Signs of Central Sensitization in Episodic and Chronic Migraine
NCT05162664
CompletedNot applicableBelgiumUniversity Ghent2021-10-15
Reliability and Validity of the Turkish Version of Sensory Hypersensivity Scale
NCT04776707
Unknown statusTurkey (Türkiye)Marmara University2021-08-16
An Observational Study of Distress, Immune Function, and Pain in HIV.
NCT04757987
CompletedSouth AfricaUniversity of Cape Town2021-02-11
Reliability and Validity of the IASP Clinical Criteria for Identifying Patients with Nociplastic Pain
NCT04730791
CompletedGreeceUniversity of Thessaly2021-02-01
The Frequency of Central Sensitization in Patients With Chronic Musculoskeletal Pain
NCT04765280
Unknown statusTurkey (Türkiye)Marmara University2021-01-01
Duloxetine As an Analgesic in Patients Without Central Sensitivity After Same Sitting Bilateral Total Knee Arthroplasty
NCT06837012
CompletedPhase 4IndiaOrthopaedic Arthroscopy Knee and Shoulder Clinic2021-01-01
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting
NCT04542798
Unknown statusNot applicableSpainHospital General Universitario de Valencia2020-10
The Effect of Palmitylethanolamide on Central and Peripheral Sensitization After Heat-induced Hyperalgesia
NCT04662827
CompletedNot applicableAustriaMedical University of Graz2020-02-09
Mindfulness to Improve Functional Outcomes in Patients With Fibromyalgia or Central Sensitization
NCT03693274
TerminatedNot applicableUnited StatesVanderbilt University Medical Center2019-01-02
Mechanisms Of Change in Adolescent Pain Self-management
NCT04043962
CompletedNot applicableUnited StatesSeattle Children's Hospital2018-11-26
Effect of Cognitive Behavioral Therapy on Chronic Low Back Pain With Sensitization
NCT03863808
CompletedNot applicableEgyptMarwa Elsayed2017-11-02

About Central Sensitisation

What is Central Sensitisation?

"Central Sensitisation" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 27 chronic pain registry records worldwide.

How is Central Sensitisation usually assessed?

Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.

What kinds of treatments are studied for Central Sensitisation?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Central Sensitisation clinical trials in Canada?

This page lists 1 registry record for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related conditions

Related interventions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.