Study of the Effects of Photobiomodulation in Patients With Osteoarthritis
No longer availableNCT03924128
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
PhotoBioModulation (PBM) is a mature science with therapeutic efficacy in humans and animals, and with excellent results in different medical specialties without side effects. However there are gaps that prevent adoption on a large scale. Recent research developed by our group and partners allowed us to understand the mechanisms of action of PBM, from Molecular Physics through Biochemistry and with consequent clinical validation, with precise, replicable and personalized therapeutic results. These findings have led to treatments for many kinds of pains with industrial predictability and accuracy, phenotypic adequacy technologies that are encapsulated, prescribed, and applied. Photobiomodulation applications cover treatments for pain, inflammation, tissue regeneration, healing, immune system activation, all of which are essential characteristics for osteoarthritis therapy. Our idea is to formulate great challenges of Photobiomodulation as a solution to osteoarthritis as follows: 1) Make PBM-based therapies as predictable as drug-based therapies; this is possible with precise dose calculation performed by our team; 2) Map the biochemical and molecular effects of PBM, including those related to gene expression; 3) Unify PBM theory by synthesizing and giving meaning to the millions of PBM data associated with osteoarthritis and correlating with clinical study to be performed under this thematic project. Overcoming these challenges, PBM will become a complementary (or supplementary) alternative to medications, physiotherapy and surgical procedures for the treatment of osteoarthritis.
Study details
- Official title
- Study of the Effects of Photobiomodulation in Patients With Osteoarthritis
- Interventions
- Device: Photobiomodulation
- Sponsor
- University of Sao Paulo
- Sex
- All
- Age range
- from 21 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Brazil
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Male and female subjects age ≥ 20 years old * Diagnosed with Osteoarthritis stages III and IV according to the American College of Rheumatology * Pain * Functional impairment for more than 3 months, able to wander with or without canes. Exclusion Criteria: * History of cancer * Unstable cardiovascular disease * uncontrolled hypertension * morbid obesity, that is, BMI ≥ 40 * terminal illness * cerebrovascular disease * dementia * heart pacemaker * superior or inferior limb fractures.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03924128