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Osteo Arthritis Knee: clinical trials and information

Osteoarthritis is the most common form of arthritis. It involves breakdown of cartilage and changes in the bone and tissues of a joint, most often in the knees, hips, hands and spine, and can cause pain, stiffness and reduced movement.
1
Trials with Canadian sites
0
Recruiting in Canada
22
Registry records worldwide

Osteo Arthritis Knee clinical trials in Canada

1 trial, recruiting first
PhaseProvinces
Pain Phenotyping in Knee OA: a Pilot Trial
NCT06066684
Unknown statusOntarioUniversity Health Network, Toronto2023-09-18

Osteo Arthritis Knee clinical trials worldwide (outside Canada)

21 trials, 4 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia
NCT06264362
Not yet recruitingNot applicableUnited StatesDrexel University2025-06-02
Optimizing Pain Self-Management in Total Knee Arthroplasty
NCT06038240
RecruitingNot applicableUnited StatesUniversity of Virginia2023-11-27
RFA or Chemical Neurolysis of the Genicular Nerves Compared to Conservative Treatment for Knee Pain Caused by OA
NCT06094660
RecruitingNot applicableNetherlandsDijklander Ziekenhuis2023-11-27
Persistent Pain in Pharmacologically or Surgical Treated Osteoarthritis: Role of Mu-Limpho Marker
NCT06637709
RecruitingItalyIRCCS San Raffaele Roma2023-11-07
Dry Cupping Therapy in Knee Osteoarthritis
NCT04331158
CompletedNot applicableBrazilUniversidade Federal do Rio Grande do Norte2023-02-01
Addition of Transcranial Direct Current Stimulation and Transcutaneous Electrical Nerve Stimulation to an Education and Exercise Program in Subjects With Chronic Pain Due to Knee Osteoarthritis
NCT05138471
CompletedNot applicableSpainUniversidad de Murcia2021-11-17
rTMS for Relieving Chronic OA Pain
NCT05097729
WithdrawnNot applicableUnited StatesNorthwestern University2021-11-15
Chronic Pain Master Protocol (CPMP): A Study of LY3526318 in Participants With Osteoarthritis
NCT05080660
CompletedPhase 2Puerto Rico, United StatesEli Lilly and Company2021-10-12
Study to Evaluate Resiniferatoxin in Patients With Knee Osteoarthritis Whose Total Knee Replacement Surgery is Delayed
NCT04386980
WithdrawnPhase 3Sorrento Therapeutics, Inc.2021-04
Robotic-assisted Total Knee Arthroplasty vs. Conventional One
NCT04611815
CompletedNot applicablePolandMedical University of Warsaw2020-12-01
ROMTECH PortableConnect Rehabilitation Device Usage Post Unilateral Total Knee Arthroplasty (TKA)
NCT04497129
CompletedNot applicableUnited StatesROM Technologies, INC2020-08-17
Pain & Aging: Combined Interventions for Fitness in the Community Study
NCT04099394
Active, not recruitingNot applicableUnited StatesUniversity of Washington2019-10-30
Platelet Rich Plasma Versus Radio Frequency for Chronic Knee Arthritis
NCT03886142
CompletedNot applicableEgyptAssiut University2018-09-27
Knee Arthritis Treatment With Autologous Fragmented Adipose Tissue and PRP - Comparison of Two Treatment Methods
NCT04321629
Unknown statusPhase 2PolandRehasport Clinic2018-07-30
Cooled RF Lesion MRI Characteristics
NCT03631030
Unknown statusNot applicableUnited StatesInternational Spine, Pain and Performance Center2018-02-25
Effect of Implanting Allogenic Cytokines Derived From Human Amniotic Membrane (HAM) and Mesenchymal Stem Cells Derived From Human Umbilical Cord Wharton's Jelly (HUMCWJ) on Pain and Functioning of Knee Osteoarthritis
NCT03337243
CompletedNot applicableUnited StatesSport and Spine Rehab Clinical Research Foundation2017-11-09
A Study to Evaluate the Analgesic Efficacy and Safety of V120083 in Subjects With Osteoarthritis (OA) of the Knee
NCT03028870
CompletedPhase 2United StatesPurdue Pharma LP2017-03-14
Anterior Knee Pain Between Unisex Knee Prosthesis VS Gender Specific Knee Prosthesis Following MIS TKA
NCT05045651
CompletedNot applicableThammasat University2014-08-01
Radiofrequency Neurotomy In Relieving Chronic Knee Pain
NCT03224637
CompletedNot applicableEgyptAssiut University2014-07
Study of the Effects of Photobiomodulation in Patients With Osteoarthritis
NCT03924128
No longer availableBrazilUniversity of Sao Paulo
Individual Patient Expanded Access IND of Autologous HB-adMSCS for the Treatment of Bilateral Knee Pain.
NCT04604288
No longer availableUnited StatesHope Biosciences Research Foundation

About Osteo Arthritis Knee

What is Osteo Arthritis Knee?

Osteoarthritis is the most common form of arthritis. It involves breakdown of cartilage and changes in the bone and tissues of a joint, most often in the knees, hips, hands and spine, and can cause pain, stiffness and reduced movement.

How is Osteo Arthritis Knee usually assessed?

Clinicians usually assess osteoarthritis through a history, physical examination of the joint and, in some cases, X-rays. Blood tests may help rule out other types of arthritis.

What kinds of treatments are studied for Osteo Arthritis Knee?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Osteo Arthritis Knee clinical trials in Canada?

This page lists 1 registry record for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related conditions

Related interventions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.