Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy
CompletedEarly phase 1NCT04019834
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to see if pre-operative regional nerve blocks compared to a placebo nerve block can decrease chronic post mastectomy pain, immediate postoperative pain and postoperative narcotic consumption.
Study details
- Official title
- Preoperative Regional Nerve Block to Decrease Acute and Chronic Post-Operative Pain and Narcotic Use Following Mastectomy
- Conditions
- Breast Cancer
- Mastectomy
- Anesthesia, Local
- Narcotic Use
- Interventions
- Drug: regional nerve block with local anesthesia of bupivacaine with steroid
- Other: Placebo regional nerveblock with normal saline
- Sponsor
- University of Alabama at Birmingham
- Start date
- 2020-07-06
- Primary completion
- 2021-11-25
- Sex
- Female
- Age range
- from 19 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Women at least 19 years old who are able to provide written and informed consent 2. Women undergoing unilateral or bilateral, simple, skin-sparing, or nipple sparing mastectomy for breast cancer (Stage 0-III) or breast cancer prevention 3. Patients with ASA class of I-III will be included Exclusion Criteria: 1. Stage IV breast cancer, morbid obesity with BMI \>45kg/m2 2. Renal insufficiency (Creatinine \>1.5 mg/dL) 3. Current chronic analgesic use (daily use for \> or equal to 4 weeks) 4. History of opioid abuse or dependence 5. Presence of chronic pain with a self-reported average pain score of 4 or greater on a pain scale of 0-10 prior to any surgical intervention 6. Incarceration 7. Pregnancy 8. Immediate autologous tissue reconstruction.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04019834