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Mechanisms of CBD for Chronic Pain

CompletedEarly phase 1NCT04044729
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

This is a study designed to examine the neurochemical mechanisms associated with Cannabidiol (CBD) versus placebo for chronic non-cancer pain.

Study details

Official title
Exploring the Mechanisms Underlying the Analgesic Properties of Cannabidiol Using Magnetic Resonance Spectroscopy
Conditions
Sponsor
University of Utah
Start date
2020-03-16
Primary completion
2024-12-01
Sex
All
Age range
from 18 Years to 50 Years
Results posted
No results posted in this snapshot
Countries
United States
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Age between 18-50 yrs. * Chronic musculoskeletal and joint pain for at least 3 months or longer. * Participants must live within a 60 mile radius of Salt Lake City, Utah to be eligible. Exclusion Criteria: * Current or past neurological illness. * Substance abuse or dependence within the prior 90 days. * Contraindication to brain MRI. * Type I and type II diabetes. * Unstable medical conditions. * Consumption of more than 2 drinks of alcohol per night. * Current pregnancy or planning to become pregnant or breastfeeding. * History of seizures or head trauma at PI discretion. * Active or history of major mental illness * Use of opioid medications in the past 30 days. * LFT results 3 times greater than the upper limit of normal at the screening. * Participants may be excluded if the PI feels they do not meet safety criteria.

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04044729