Effects of Intramuscular (IM) Oxytocin on Pupil Diameter and Heart Rate Variability (HRV)
CompletedPhase 4NCT04105998
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The goal of this study is to test the effects of oxytocin on heart rate variability and pupil diameter, both of which have subtle effects on the activity rate of the autonomic nervous system.
Study details
- Official title
- Effects of Intramuscular Oxytocin on Pupil Diameter and Heart Rate Variability
- Conditions
- Interventions
- Sponsor
- Wake Forest University Health Sciences
- Start date
- 2019-10-24
- Primary completion
- 2021-11-01
- Sex
- All
- Age range
- from 18 Years to 66 Years
- Healthy volunteers
- true
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Male or female \> 18 and \< 66 years of age, * Body Mass Index (BMI) \<40 * Generally in good health as determined by the Principal Investigator based on prior medical history * Normal blood pressure and resting heart rate without medication Exclusion Criteria: * Hypersensitivity, allergy, or significant reaction to any ingredient of Pitocin® * Any disease, diagnosis, or condition (medical or surgical) that, in the opinion of the Principal Investigator, would place the subject at increased risk * Women who are pregnant (positive result for serum pregnancy test at screening visit), * Women who are currently nursing or lactating, women that have been pregnant within 2 years. * Neuropathy, chronic pain, diabetes mellitus, or taking benzodiazepines or pain medications on a daily basis. * Previous eye surgery, eye medications, cataracts
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04105998