A Study of the Safety, Tolerability and Pharmacokinetics of MEDI0618 in Healthy Volunteers
CompletedPhase 1NCT04198558
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This is a randomised, placebo-controlled study of the safety and tolerability of single doses of MEDI0618 in healthy volunteer subjects.
Study details
- Official title
- A Randomised, Double-blind, Placebo-controlled Study of the Safety, Tolerability, and Pharmacokinetics of Single Ascending Doses of MEDI0618 in Healthy Male and Female Volunteers
- Conditions
- Interventions
- Drug: MEDI0618
- Drug: Placebo
- Sponsor
- AstraZeneca
- Start date
- 2019-11-29
- Primary completion
- 2022-02-23
- Sex
- All
- Age range
- from 18 Years to 55 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Germany
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Healthy men and women of non-childbearing potential aged 18 to 55 years * Normal 12-lead ECG at screening and on day of dosing * Physical examinations with no significant findings at screening * Be able to understand and comply with protocol requirements Exclusion Criteria: * Participation in another clinical study with an investigational product (IP) within half-lives of the IP or 3 months, whichever is longer, prior to screening * Requires treatment with another biological therapeutic agent * Inability to comply with study-related requirements * History of severe allergy or hypersensitivity reactions * History of significant psychiatric disorder * Presence of any clinically significant illness * History of cancer * Any clinically important abnormality physical examination, vital signs, ECG or laboratory test
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04198558