Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
SuspendedNCT04306939
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect clinical decision making. The study will evaluate risk factors and co-variants, including genetic variants that are associated with disease progression such as pain, inflammation, organ dysfunction, disability and quality of life.
Study details
- Official title
- Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
- Conditions
- Chronic Pancreatitis
- Inflammatory Bowel Diseases
- Hepatitis
- NASH - Nonalcoholic Steatohepatitis
- Acute Pancreatitis
- Rheumatoid Arthritis
- Diabetes Mellitus
- Dyslipidemias
- Multiple Sclerosis
- Irritable Bowel Syndrome
- Chronic Pain
- Chronic Disease
- Chronic Kidney Diseases
- Crohn Disease
- Celiac Disease
- Biliary Cirrhosis
- Bile Acid Synthesis Defect
- Gastritis
- Cholecystitis
- Cholelithiases
- Ipmn
- Cyst Pancreas
- Cystic Fibrosis
- Pancreatic Exocrine Insufficiency
- Diarrhea Chronic
- Constipation - Functional
- Constipation Chronic Idiopathic
- Interventions
- Other: venipuncture
- Behavioral: Questionnaires
- Other: Additional Sample Collections
- Sponsor
- University of Pittsburgh
- Start date
- 2014-11-01
- Primary completion
- 2026-12
- Sex
- All
- Age range
- from 12 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: Case Subjects * Clinical diagnosis of a chronic disease or disorder (ex. pancreatitis, hepatitis or fatty liver, inflammatory bowel disease, irritable bowel syndrome, diarrhea, constipation, chronic pain syndromes, diabetes, hypertension, cardiovascular disease, chronic kidney disease, chronic neurologic disorders, rheumatological disorders, endocrine disorders, chronic pulmonary diseases, sinorespiratory disorders, chronic skin diseases, cancers and related disorders) * Ability to read and write in English; * Ability to provide informed consent Control Subjects • UPMC patients age 12 years without a chronic disorder. Exclusion Criteria: * Chronic infectious disease as the primary medical problem * Less than 12 years of age * Inability of the subject to understand the protocol * Inability to the subject provide informed consent
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04306939