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Multiple Sclerosis: clinical trials and information

"Multiple Sclerosis" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 29 chronic pain registry records worldwide.
1
Trials with Canadian sites
0
Recruiting in Canada
29
Registry records worldwide

Multiple Sclerosis clinical trials in Canada

1 trial, recruiting first
PhaseProvinces
Detecting and Addressing Preclinical Disability
NCT01979081
CompletedOntarioMcMaster University2013-01

Multiple Sclerosis clinical trials worldwide (outside Canada)

28 trials, 4 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Emerging Indications for Hyperbaric Oxygen Treatment
NCT07240649
Not yet recruitingPhase 4Jay C. Buckey Jr.2026-11
Pain Phenotypes in Individuals With Multiple Sclerosis
NCT07766213
Not yet recruitingTurkey (Türkiye)Kutahya Health Sciences University2026-08-15
Dry Needling in Multiple Sclerosis
NCT07615725
RecruitingNot applicableUnited StatesUniversity of South Florida2026-05-08
EXpain Trial - Exercise an a Non-pharmacological Pain-relieving Treatment in People With Multiple Sclerosis
NCT07342777
RecruitingNot applicableDenmarkUniversity of Aarhus2026-01-15
Usability of the MeTime MS App
NCT07123272
CompletedNot applicableUnited StatesUniversity of Michigan2025-03-17
Pilates Versus Eccentric Exercises on Multiple Sclerosis
NCT06524089
CompletedNot applicableEgyptCairo University2024-07-30
Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
NCT06071949
Unknown statusPhase 3GermanyApurano Pharmaceuticals GmbH2023-11-02
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
NCT06072001
Unknown statusPhase 3GermanyApurano Pharmaceuticals GmbH2023-11-02
The Living With a Long-Term Condition Study
NCT06072287
Unknown statusUnited KingdomKing's College London2023-06-28
Performance and Long-term Safety of FlowOx2.0™ in Patients With Multiple Sclerosis - Impact on Spasticity and Pain
NCT05562453
CompletedNot applicableSwedenOtivio AS2022-10-04
Quest to Analyze One Thousand Humans Meditating
NCT06583395
Enrolling by invitationUnited StatesTobias Moeller-Bertram2021-12-05
Telehealth Pain Self-Management for Employed Adults
NCT04248725
CompletedNot applicableUnited StatesUniversity of Washington2020-03-02
Arts & Health Education to Improve Health, Resilience, and Well-Being
NCT04154579
TerminatedNot applicableUnited StatesLisa Gallagher2019-07-01
Neurology Inpatient Clinical Education Trial
NCT03826056
CompletedNot applicableUnited StatesDartmouth-Hitchcock Medical Center2019-02-01
Outcomes Mandate National Integration With Cannabis as Medicine
NCT03944447
Unknown statusPhase 2United StatesOMNI Medical Services, LLC2018-12-01
MBCT and CBT for Chronic Pain in Multiple Sclerosis
NCT03782246
Unknown statusNot applicableUnited StatesUniversity of Washington2018-11-28
Virtual Reality (VR) to Improve Quality of Life in Patients Diagnosed With Neurological Disorders
NCT03606668
CompletedNot applicableUnited StatesNYU Langone Health2018-06-20
MS Symptom Management Study
NCT02474940
CompletedNot applicableUnited StatesUniversity of Washington2015-06
PatientSpot Formerly Known as ArthritisPower
NCT03840928
Unknown statusUnited StatesGlobal Healthy Living Foundation2015-04-01
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
NCT04306939
SuspendedUnited StatesUniversity of Pittsburgh2014-11-01
Spinal Direct Current Stimulation Effects on Pain in Multiple Sclerosis
NCT02331654
Unknown statusNot applicableItalyIRCCS National Neurological Institute "C. Mondino" Foundation2013-11
Comparison of the Efficacy and Mechanisms for MBCT and CT for Multiple Sclerosis (MS) Chronic Pain
NCT02012439
CompletedPhase 1, Phase 2United StatesUniversity of Washington2013-10
Power Over Pain (POP) Study
NCT01800604
CompletedNot applicableUnited StatesUniversity of Washington2013-02
Telephone Intervention for Pain Study (TIPS)
NCT00663663
CompletedNot applicableUnited StatesUniversity of Washington2009-09
Trial of Analgesia With Lidocaine or Extended-release Oxycodone for Neuropathic Pain Treatment in Multiple Sclerosis
NCT00414453
TerminatedPhase 4United StatesUniversity of Rochester2007-01
Cognitive-behavior Therapy for MS-Related Chronic Pain
NCT00323271
CompletedNot applicableUnited StatesUS Department of Veterans Affairs2006-07
A Study to Evaluate the Effects of Cannabis Based Medicine in Patients With Pain of Neurological Origin
NCT01606176
CompletedPhase 3United KingdomJazz Pharmaceuticals2002-03
Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
NCT03847753
CompletedUniversity of Aarhus2000-01-01

About Multiple Sclerosis

What is Multiple Sclerosis?

"Multiple Sclerosis" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 29 chronic pain registry records worldwide.

How is Multiple Sclerosis usually assessed?

Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.

What kinds of treatments are studied for Multiple Sclerosis?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Multiple Sclerosis clinical trials in Canada?

This page lists 1 registry record for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related interventions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.