Multiple Sclerosis: clinical trials and information
Multiple Sclerosis clinical trials in Canada
| Phase | Provinces | ||||
|---|---|---|---|---|---|
| Detecting and Addressing Preclinical Disability NCT01979081 | Completed | Ontario | McMaster University | 2013-01 |
Multiple Sclerosis clinical trials worldwide (outside Canada)
28 trials, 4 recruiting or not yet recruiting. Recruiting first.
| Phase | Countries | ||||
|---|---|---|---|---|---|
| Emerging Indications for Hyperbaric Oxygen Treatment NCT07240649 | Not yet recruiting | Phase 4 | Jay C. Buckey Jr. | 2026-11 | |
| Pain Phenotypes in Individuals With Multiple Sclerosis NCT07766213 | Not yet recruiting | Turkey (Türkiye) | Kutahya Health Sciences University | 2026-08-15 | |
| Dry Needling in Multiple Sclerosis NCT07615725 | Recruiting | Not applicable | United States | University of South Florida | 2026-05-08 |
| EXpain Trial - Exercise an a Non-pharmacological Pain-relieving Treatment in People With Multiple Sclerosis NCT07342777 | Recruiting | Not applicable | Denmark | University of Aarhus | 2026-01-15 |
| Usability of the MeTime MS App NCT07123272 | Completed | Not applicable | United States | University of Michigan | 2025-03-17 |
| Pilates Versus Eccentric Exercises on Multiple Sclerosis NCT06524089 | Completed | Not applicable | Egypt | Cairo University | 2024-07-30 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis NCT06071949 | Unknown status | Phase 3 | Germany | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis NCT06072001 | Unknown status | Phase 3 | Germany | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| The Living With a Long-Term Condition Study NCT06072287 | Unknown status | United Kingdom | King's College London | 2023-06-28 | |
| Performance and Long-term Safety of FlowOx2.0™ in Patients With Multiple Sclerosis - Impact on Spasticity and Pain NCT05562453 | Completed | Not applicable | Sweden | Otivio AS | 2022-10-04 |
| Quest to Analyze One Thousand Humans Meditating NCT06583395 | Enrolling by invitation | United States | Tobias Moeller-Bertram | 2021-12-05 | |
| Telehealth Pain Self-Management for Employed Adults NCT04248725 | Completed | Not applicable | United States | University of Washington | 2020-03-02 |
| Arts & Health Education to Improve Health, Resilience, and Well-Being NCT04154579 | Terminated | Not applicable | United States | Lisa Gallagher | 2019-07-01 |
| Neurology Inpatient Clinical Education Trial NCT03826056 | Completed | Not applicable | United States | Dartmouth-Hitchcock Medical Center | 2019-02-01 |
| Outcomes Mandate National Integration With Cannabis as Medicine NCT03944447 | Unknown status | Phase 2 | United States | OMNI Medical Services, LLC | 2018-12-01 |
| MBCT and CBT for Chronic Pain in Multiple Sclerosis NCT03782246 | Unknown status | Not applicable | United States | University of Washington | 2018-11-28 |
| Virtual Reality (VR) to Improve Quality of Life in Patients Diagnosed With Neurological Disorders NCT03606668 | Completed | Not applicable | United States | NYU Langone Health | 2018-06-20 |
| MS Symptom Management Study NCT02474940 | Completed | Not applicable | United States | University of Washington | 2015-06 |
| PatientSpot Formerly Known as ArthritisPower NCT03840928 | Unknown status | United States | Global Healthy Living Foundation | 2015-04-01 | |
| Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study NCT04306939 | Suspended | United States | University of Pittsburgh | 2014-11-01 | |
| Spinal Direct Current Stimulation Effects on Pain in Multiple Sclerosis NCT02331654 | Unknown status | Not applicable | Italy | IRCCS National Neurological Institute "C. Mondino" Foundation | 2013-11 |
| Comparison of the Efficacy and Mechanisms for MBCT and CT for Multiple Sclerosis (MS) Chronic Pain NCT02012439 | Completed | Phase 1, Phase 2 | United States | University of Washington | 2013-10 |
| Power Over Pain (POP) Study NCT01800604 | Completed | Not applicable | United States | University of Washington | 2013-02 |
| Telephone Intervention for Pain Study (TIPS) NCT00663663 | Completed | Not applicable | United States | University of Washington | 2009-09 |
| Trial of Analgesia With Lidocaine or Extended-release Oxycodone for Neuropathic Pain Treatment in Multiple Sclerosis NCT00414453 | Terminated | Phase 4 | United States | University of Rochester | 2007-01 |
| Cognitive-behavior Therapy for MS-Related Chronic Pain NCT00323271 | Completed | Not applicable | United States | US Department of Veterans Affairs | 2006-07 |
| A Study to Evaluate the Effects of Cannabis Based Medicine in Patients With Pain of Neurological Origin NCT01606176 | Completed | Phase 3 | United Kingdom | Jazz Pharmaceuticals | 2002-03 |
| Exploring the Comorbidity Between Mental Disorders and General Medical Conditions NCT03847753 | Completed | University of Aarhus | 2000-01-01 |
About Multiple Sclerosis
What is Multiple Sclerosis?
"Multiple Sclerosis" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 29 chronic pain registry records worldwide.
How is Multiple Sclerosis usually assessed?
Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.
What kinds of treatments are studied for Multiple Sclerosis?
Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.
How can I find Multiple Sclerosis clinical trials in Canada?
This page lists 1 registry record for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.
Related interventions
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.