Comparison Erect Spine in Cardiac Surgery
Unknown statusPhase 3NCT04313959
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Open cardiac surgeries are characterized by the increased use of opioids and longer extubation times, being post-sternotomy pain one of the causes of greater patient discomfort, plexus blockages have been used more frequently given the good results of anatomical studies and case series that are just beginning to be published. however, there is not enough data to convince the scientific community of its advantages, continuing to carry out its performance due to lack of evidence. Dexamethasone also shows an excellent result blocking the inflammatory chain and it was evidenced that it prolongs the time of blockages when used perineurally in the plexus blockages. This study wants to show the improvement of pain in patients who undergo this type of surgery and also show the advantages of a longer blockage, which can reduce use of analgesic and opioids, as well as decrease the time of hospitalization This is a double-blinded, randomized, clinical trial designed to determine the efficacy of spine erector whit dexamethasone gives more duration of the blockage and less pain after cardiac surgery.
Study details
- Official title
- Comparison of Two Anesthetic Techniques in Blocking the Erector Plane of the Spine Bilateral in Cardiac Surgery: a Prospective Randomized Double-blinded Clinical Trial
- Conditions
- Spine Erector
- Cardiac Surgery
- Acute Pain
- Chronic Pain
- Interventions
- Drug: Ropivacaine 0.2% Injectable Solution
- Drug: Ropivacaine 0.2% + Dexamethasone
- Sponsor
- Instituto do Coracao
- Start date
- 2022-01-20
- Primary completion
- 2023-02-25
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Brazil
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Coronary artery bypass graft with cardiopulmonary bypass * Left ventricular ejection fraction ≥ 45% Exclusion Criteria: * Reoperation * Low cardiac output syndrome * Preoperative coagulopathy * Presence of ventricular assist device other than intraaortic ballon pump * Emergency procedures * Bacterial or fungal infection in the preceding 30 days * Active neoplasia * Allergy or intolerance to steroids * Allergy to ropivacaine * Patient refusal * Participation in other study
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04313959