Opioid Approach Bias Modification
CompletedNot applicableNCT04436926
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
To investigate the neurobiological mechanisms underlying opioid approach bias during a pilot RCT of opioid approach bias modification. The investigators are combining novel ultra-high field MRI technology with the promising treatment of modifying cognitive bias away from detrimental prescription drug use will generate novel neural data and potentially yield a new therapeutic tool to reduce problematic opioid use.
Study details
- Official title
- The Neural Basis of Approach Bias Modification in Opioid Users With Chronic Pain
- Conditions
- Interventions
- Behavioral: opioid approach bias modification
- Behavioral: sham training
- Sponsor
- University of California, San Francisco
- Start date
- 2021-03-01
- Primary completion
- 2023-10-30
- Sex
- All
- Age range
- from 18 Years to 69 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Male and female veterans eligible for VA services * Ages 18-69 * Chronic pain (current pain lasting ≥ 90 days) * Prescribed chronic opioids (≥ 90 days in past year) * High risk for opioid-related averse outcomes (≥ 20mg morphine equivalent daily dose). Exclusion Criteria: * Psychotic, bipolar disorders or other psychiatric disorders judged to be unstable by the PI * Current or past history of the following: intrinsic cerebral tumors, cerebrovascular accident/disease, brain aneurysm, arteriovenous malformations, surgical implantation of neurostimulators or cardiac pacemakers, demyelinating and neurodegenerative diseases, penetrating traumatic brain injury, and any other MRI contraindications. * No female participant will be pregnant or actively attempting to conceive to prevent any unnecessary exposure to high magnetic fields or radio frequency energy to the unborn child. * Concurrent participation in a treatment study * Moderately Severe/Severe withdrawal from opioids based on a score of 25 or more on the Clinical Opiate Withdrawal Scale (COWS)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04436926