Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients
CompletedNot applicableNCT04603417
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This study is designed to find behavioral and neurophysiological correlates of pain avoidance behavior among chronic pain patients, controlling for risk for opioid use disorder. Further, traits and risk factors that contribute to pain avoidance behavior will be investigated. The knowledge gained will broaden the current understanding of mechanisms involved in pain avoidance behavior in chronic pain patients, and help devise novel interventions.
Study details
- Official title
- Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients
- Conditions
- Interventions
- Diagnostic test: Electroencephalography (EEG)/Magnetoencephalography (MEG)/MRI
- Sponsor
- The Cleveland Clinic
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Start date
- 2020-08-15
- Primary completion
- 2024-04-30
- Sex
- All
- Age range
- from 18 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * 18 years and older * Diagnosis of CRPS I, CRPS II * Six months or more of medically refractory severe pain * Average daily pain for the past 30 days reported as ≥ 5 on a 0 - 10 scale * Presence of allodynia * Unilateral pain or pain affecting predominantly one extremity. Predominantly will be operationally defined at \>=75 of pain on one extremity. * Willingness to complete behavioral, clinical and neurophysiological measurement procedures * Able to provide informed consent * Able to undergo structural brain MRI Exclusion Criteria: * 17 years and younger * All other pain diagnosis * Less than six months or more of medically refractory severe pain * Average daily pain for the past 30 days reported as \< 5 on a 0 - 10 scale * Absence of allodynia * Bilateral pain * Unwillingness to complete behavioral, clinical and neurophysiological measurement procedures * Unable to provide informed consent * Claustrophobic or unable to undergo MRI, MEG or unsafe to undergo MRI (i.e. due to MRI unsafe medical implants).
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04603417