Determinants of Depression and Its Impact on Quality of Life in Patients With Chronic Pancreatitis
CompletedNCT04867304
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Chronic pancreatitis (CP) is associated with recurrent intractable abdominal pain, pancreatic exocrine insufficiency and endocrine dysfunction. Very few studies had evaluated the quality of life in CP, and even a fewer have assessed the mental status in these patients. In the current study, we proposed to evaluate the the relationship between pain, quality of life and depression status in two large independent cohorts of patients with CP. We also proposed to evaluate the brain metabolites in the right and left anterior cingulate cortex, basal ganglia, hippocampus and prefrontal cortex using magnetic resonance spectroscopy. We further proposed to evaluate the pasta metabolites and look for associations with the mental state. Finally, we proposed to evaluate how CP related education of the patients could impact on their mental status and response to interventions on pain.
Study details
- Official title
- Determinants of Depression and Its Impact on Quality of Life in Patients With Chronic Pancreatitis
- Interventions
- Other: Patient education about chronic pancreatitis.
- Sponsor
- Asian Institute of Gastroenterology, India
- Start date
- 2018-02-01
- Primary completion
- 2020-01-31
- Sex
- All
- Age range
- from 18 Years to 60 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- India
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
A. Inclusion Criteria: * Age 18-60yrs * Both genders * Documented CP for at least 3 years * Capable and willing to provide informed consent B. Exclusion Criteria: * Acute exacerbation of pancreatitis * Pancreatic malignancy * On anti-depressant and antipsychotic medications * Concomitant psychiatric illness (other than depression) * Pancreatic malignancy * Major co-morbidities * Pregnancy and lactation
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04867304