Mobile & Online-Based Interventions to Lessen Pain
CompletedPhase 3NCT05152134
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The investigators will implement an international 2-arm online pragmatic feasibility randomized controlled trial (RCT) of a digital pain relief skills intervention "Empowered Relief: On-Demand" to reduce pain metrics, opioid craving, and opioid misuse. They will compare Empowered Relief to a no-skills digital health education ("Living Better") intervention in community-based individuals with comorbid chronic pain and prescription opioid misuse (N=220). Completion of the brief post-treatment survey is a binary measure of treatment engagement; treatment feasibility and appraisal are assessed with three items (satisfaction, perceived utility, and likelihood to use skills learned). Electronic surveys will measure opioid misuse behaviors, craving, and use; and pain intensity and psychological status at: baseline, immediately post-treatment; at post-treatment weeks 1 and 2; and months 1, 2, and 3.
Study details
- Official title
- Mobile & Online-Based Interventions to Lessen Pain (MOBILE Relief) in People With Prescription Opioid Misuse
- Interventions
- Behavioral: Empowered Relief On-Demand
- Behavioral: Health Education
- Sponsor
- Stanford University
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Start date
- 2023-08-23
- Primary completion
- 2025-08-15
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Male and females 18 years of age or older * Chronic non-cancer pain (at least 6 months in duration) * Average pain intensity of at least 3 on the PROMIS SFV1.0 Pain Intensity 1a * Daily prescription opioid use (at least 10 morphine milliequivalent daily dose; MEDD) for at least 3 months * Opioid misuse (at least 6 on the Current Opioid Misuse Measure; COMM) * English fluency * Internet access Exclusion Criteria: * Gross cognitive impairment * Inability to complete study electronic surveys * Cannot currently be enrolled in a study or trial with Empowered Relief as a treatment/intervention
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05152134