Skip to content

Opioid Use Disorder: clinical trials and information

"Opioid Use Disorder" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 35 chronic pain registry records worldwide.
1
Trials with Canadian sites
0
Recruiting in Canada
35
Registry records worldwide

Opioid Use Disorder clinical trials in Canada

1 trial, recruiting first
PhaseProvinces
Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial
NCT06028126
CompletedNot applicableAlberta, British Columbia, Nova Scotia, OntarioUnity Health Toronto2023-09-08

Opioid Use Disorder clinical trials worldwide (outside Canada)

34 trials, 9 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Digital Treatment for Chronic Pain and Addiction in Veterans With Opioid Use Disorder Receiving Buprenorphine
NCT07361432
Not yet recruitingPhase 3United StatesVA Office of Research and Development2026-11-02
A Study of Cebranopadol for Opioid Withdrawal Symptoms in Adults With Chronic Pain
NCT07874620
Not yet recruitingPhase 2United StatesAdneuris Therapeutics, Inc.2026-09
Low-Intensity Focused Ultrasound and the Complex Patient
NCT06297200
RecruitingNot applicableUnited StatesVirginia Polytechnic Institute and State University2024-12-04
Adolescent Outcomes of Post-operative Opioid EXposure
NCT06350409
RecruitingUnited StatesSharon Levy2024-11-12
Combined THC and CBD for OUD and Chronic Pain
NCT06544291
RecruitingPhase 2United StatesYale University2024-10-22
Focused Ultrasound for the Complex Patient
NCT06453109
RecruitingNot applicableUnited StatesWashington D.C. Veterans Affairs Medical Center2024-04-29
Translation and Validation of the COMM and ASI-SR
NCT06084520
RecruitingSwedenUppsala University2023-12-01
Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial
NCT06565416
RecruitingNot applicableUnited StatesUniversity of New Mexico2023-06-01
Divided or Single Exposure (DOSE) Study
NCT05459402
RecruitingPhase 2, Phase 3United StatesUniversity of Maryland, Baltimore2023-02-21
Transition From Acute to Chronic Opioid Use and Chronic Pain
NCT07211399
WithdrawnEarly phase 1United StatesJacques E. Chelly2026-07-01
Mindfulness-Based Ecological Momentary Intervention for Opioid Use Disorder and Chronic Pain
NCT06947122
CompletedNot applicableUnited StatesArizona State University2026-02-10
Emotional Awareness and Expression Therapy for Chronic Pain and Opioid Use Disorder
NCT06865560
CompletedNot applicableUnited StatesUniversity of Michigan2025-06-03
The Acupuncture for Pain, Opioid Use Disorder and Mood
NCT06543355
CompletedNot applicableUnited StatesAlbert Einstein College of Medicine2025-01-06
Pain Self-Management and Treatment Engagement for Patients Taking Opioids
NCT06855732
Active, not recruitingNot applicableUnited StatesUniversity of Pittsburgh2024-11-25
Assessing the Efficacy of Self-Driven Repetitive Artmaking Practice
NCT06554431
CompletedNot applicableUnited StatesMontefiore Medical Center2024-07-02
Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment
NCT06367387
Active, not recruitingPhase 4United StatesErin Winstanley2024-05-28
Mobile & Online-Based Interventions to Lessen Pain
NCT05152134
CompletedPhase 3United StatesStanford University2023-08-23
Stepped Care for Patients to Optimize Whole Recovery
NCT05155163
Active, not recruitingNot applicableUnited StatesYale University2023-06-28
Increasing Access to Evidence-based Treatment for Chronic Pain and Opioid Use Disorder: Adapting Acceptance and Commitment Therapy for Opioid Treatment Programs
NCT06581276
CompletedNot applicableUnited StatesMontefiore Medical Center2023-06-23
Pain Care at Home to Amplify Function (Pain CHAMP)
NCT05333341
Active, not recruitingNot applicableUnited StatesYale University2023-06-16
Tai Chi Easy for Opioid Use Disorder, Anxiety, and Chronic Pain
NCT05850533
CompletedNot applicableUnited StatesAsana Recovery2023-05-22
Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial
NCT05571917
Active, not recruitingNot applicableUnited StatesUniversity of New Mexico2023-05-05
Auricular Acupressure as a Non-Opioid Adjuvant in Opioid Tolerant Patients
NCT05711537
CompletedNot applicableUnited StatesWake Forest University Health Sciences2023-04-17
STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis
NCT05603702
Active, not recruitingPhase 1United StatesIndiana University2023-03-17
IMPOWR-ME Project 1: Trial of Yoga and Physical Therapy Onsite at Opioid Treatment Programs
NCT05492825
Active, not recruitingNot applicableUnited StatesAlbert Einstein College of Medicine2023-02-27
Virtual Reality for Chronic Pain and Opioid Use Disorder Pilot
NCT05546749
CompletedNot applicableUnited StatesAlbert Einstein College of Medicine2023-02-08
Computer Based Treatment for Cognitive Behavioral Therapy and Cooperative Pain Education and Self-Management
NCT05204576
CompletedNot applicableUnited StatesYale University2022-07-15
An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment
NCT05051644
CompletedPhase 1United StatesVA Office of Research and Development2022-04-01
Cannabidiol in Opioid Use Disorder and Chronic Pain
NCT04587791
CompletedEarly phase 1United StatesYale University2021-12-08
Pain and Opioid Management in Older Adults
NCT05037682
Unknown statusNot applicableUnited StatesUniversity of Oklahoma2020-09-30
Long-Term Opioid Therapy in Chronic Non-Cancer Pain: Risks and Benefits
NCT06063902
Enrolling by invitationSwedenUppsala University2019-01-14
Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans
NCT02657317
CompletedNot applicableUnited StatesThe University of Texas Health Science Center at San Antonio2016-04-04
Phase II Pharmacokinetics Study of CAM2038
NCT02710526
CompletedPhase 2United StatesBraeburn Pharmaceuticals2015-02
Buprenorphine Treatment: A Safe Alternative for Opioid Dependent Pain Patients
NCT01841931
TerminatedPhase 4United StatesTheresa Jacob, PhD, MPH2013-02

About Opioid Use Disorder

What is Opioid Use Disorder?

"Opioid Use Disorder" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 35 chronic pain registry records worldwide.

How is Opioid Use Disorder usually assessed?

Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.

What kinds of treatments are studied for Opioid Use Disorder?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Opioid Use Disorder clinical trials in Canada?

This page lists 1 registry record for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related conditions

Related interventions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.