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Embodied Virtual Reality for Chronic Pain

CompletedNot applicableNCT05160038
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

Virtual reality creates interactive, multimodal sensory stimuli that have demonstrated considerable success in reducing pain. Much research so far has focused on VR's ability to shift patients' attention away from pain; however, these methods provide only transient relief through means of distraction and therefore do not offer long-term analgesic remediation. An alternative and promising approach is to utilize VR as an embodied simulation technique, where virtual body illusions are employed as tools to improve body perception and produce potentially more enduring analgesia. Disturbances in body perception (i.e., alterations in the way the body is perceived) are increasingly acknowledged as a pertinent feature of chronic pain, and include aberrations in perceived shape, size, or color that differ from objective assessment. The degree of body perception distortion positively correlates with pain, and prior interventions have evinced that treatments aimed at reducing body perception distortions correspondingly ameliorate pain. Several recent experimental research studies have demonstrated the analgesic efficacy of body illusions in a range of pain conditions. Immersive VR multisensory feedback training signifies a promising new avenue for the potential treatment of chronic pain by supporting the design of targeted virtual environments to alter (distorted) body perceptions. Various illusions have been described to alter pain perception; however, they. Have not been directly compared to each other. The multimodal stimulus control of VR enables physical-to-virtual body transfer illusions, resulting in the feeling that the virtual body is one's own. These virtual body illusions can modulate body perception with ease and could therefore be used to alter the perceived properties of pain, consequently utilizing a virtual avatar to specifically shape interactive processing between central and peripheral mechanisms.

Study details

Official title
Embodied Virtual Reality for Chronic Pain
Conditions
  • Complex Regional Pain Syndromes
  • Complex Regional Pain Syndrome Type I of the Upper Limb
  • Complex Regional Pain Syndrome I (CRPS I)
  • Complex Regional Pain Syndrome I of Upper Limb
  • Complex Regional Pain Syndrome Type II
  • Complex Regional Pain Syndrome II of Upper Limb
  • Peripheral Nerve Injury Upper Limb
  • Osteoarthritis Hand
  • Osteoarthritis Finger
Interventions
  • Device: Embodied virtual reality
Sponsor
University of Zurich
Collaborators
Balgrist University Hospital
Start date
2021-05-31
Primary completion
2024-08-31
Sex
All
Age range
from 18 Years to 80 Years
Results posted
No results posted in this snapshot
Countries
Switzerland
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Written informed consent by the participants * Presence of one of the following chronic pain conditions of the upper limbs: osteoarthritis (OA), complex regional pain syndrome (CRPS) Exclusion Criteria: * Inability to follow study procedures, e.g., due to language problems, psychological disorders, dementia, etc. of the participant * Extreme motion sickness, nausea, or dizziness to the virtual simulations * Currently pregnant or breastfeeding women * High risk populations for Covid-19 (i.e., high blood pressure, chronic respiratory condition, diabetes, presence of autoimmune disease, cardiovascular disease, presence of cancer)

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05160038