Improving Pain Disability With the Use of Oral Cannabinoids
CompletedNot applicableNCT05351905
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Brief summary (from the registry)
The investigators are conducting a pilot (i.e. a small study) in order to find out the effectiveness and safety of medical cannabis in the management of chronic pain. At the end of this 3 month study, investigators will gather information on how easy it is for patients to enroll and complete the entire study. The results of this pilot study will help the study team design a larger randomized controlled trial.
Study details
- Official title
- A Single-centre, Pilot, Randomized Controlled Trial of Oral Cannabinoids for Improving Pain Disability in Patients With Chronic Pain
- Conditions
- Chronic Pain
- Opioid Use
- Cannabis
- Interventions
- Drug: CBD oil ( MPL-001)
- Drug: CDB+THC oil (MPL-005)
- Drug: Placebo oil
- Sponsor
- University Health Network, Toronto
- Start date
- 2022-11-22
- Primary completion
- 2025-12-31
- Sex
- All
- Age range
- from 25 Years
- Results posted
- No results posted in this snapshot
- Countries
- Canada
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Age ≥ 25 years 2. Able to understand and read English 3. Experiencing chronic, non-palliative pain Exclusion Criteria: 1. Use of nabilone, nabiximols or cannabis in the 30 days preceding study recruitment 2. Known allergy to cannabis or any cannabinoid 3. Serious ongoing medical issues (i.e., lung, liver, kidney or heart disease) that in the opinion of the Investigator would compromise the safety of the patient 4. Current uncontrolled serious mental disorders such as schizophrenia, or psychosis 5. Currently pregnant or breast-feeding (a negative urine pregnancy test must be obtained for women of child bearing potential during pretreatment evaluation) 6. Men and women planning to start a family in the next 12 weeks 7. Has declared a current alcohol or substance use disorder (excluding opioid use disorder) 8. Currently using Methadone or Buprenorphine 9. Patients who are naïve to pain treatments
Canadian sites (1)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05351905