Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes
CompletedNCT05491499
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This work will answer two critical questions: 1) Does intensive interdisciplinary pain treatment (IIPT) involving aerobic exercise help normalize pain processing in youth with chronic pain syndromes and 2) Are aerobic fitness levels and the ability to modulate pain inter-related? Currently, medications are ineffective for improving pain and disability in youth with chronic pain syndromes and identifying non-pharmacologic treatments, such as IIPT, that help strengthen the nervous system's ability to modulate or turn pain signals down will improve outcomes and quality of life for youth suffering from chronic pain. This study will help determine whether exercise based IIPT leads to physiologic improvements in how pain is processed, specifically if youth with chronic pain can better turn pain down during the offset analgesia test after an exercise based IIPT treatment, and also help elucidate the link between a child's aerobic fitness and their ability to modulate pain.
Study details
- Official title
- Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes
- Conditions
- Chronic Pain Syndrome
- Fibromyalgia
- Chronic Headache Disorder
- Functional Abdominal Pain Syndrome
- Complex Regional Pain Syndromes
- Sponsor
- Boston Children's Hospital
- Collaborators
- APTA Pediatrics
- Start date
- 2022-10-17
- Primary completion
- 2023-11-30
- Sex
- All
- Age range
- from 10 Years to 17 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria:\] i) age 10-17 years ii) first test completed within 5 days of admission iii) established diagnosis of primary or secondary chronic pain iv) report of constant moderate pain (≥ 5/10 on a numeric rating scale of 0-10 points) for at least 3 months duration v) stable use of medications for at least one week prior to the study visit. Exclusion Criteria: i) presence of allodynia in either upper extremity ii) a history of central nervous system, heart, kidney, liver and respiratory system diseases, and psychiatric disorders (e.g., bipolar, conversion, psychosis) iii) reported consumption of alcohol, cannabis or tobacco products iv) unable to read English or follow testing instructions v) intolerant to the thermal test stimulus, or vi) no pain reported at maximum stimulus (48ºC).
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05491499