The Relationship Between Chronic OA Pain and Cognition Deficits in OA Patients.
CompletedNCT05570240
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The goal of this observational study is to learn about the association between pain characteristics and cognitive functions in chronic knee osteoarthritis. The main questions it aims to answer are: 1. If pain characteristics affect cognitive functions in severe knee OA patients? 2. If concentration of neuroinflammation mediators were raised in severe knee OA patients with comparing with control group participants? Participants will receive pain and cognition questionnaire before surgery and their blood and CSF will be collected for further analysis of neuroinflammation mediators.
Study details
- Official title
- The Relationship Between Chronic OA Pain and Cognition Deficits in OA Patients.
- Conditions
- Knee Osteoarthritis
- Neuroinflammatory Response
- Sponsor
- Kaohsiung Veterans General Hospital.
- Start date
- 2019-08-07
- Primary completion
- 2021-04-21
- Sex
- All
- Age range
- from 20 Years to 86 Years
- Results posted
- No results posted in this snapshot
- Countries
- Taiwan
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * OA patients who were scheduled to receive elective surgery which need spinal anesthesia. * Age is more than 20 years old. * American Society of Anesthesiologists (ASA) class I-III. Exclusion Criteria: * Unwilling to participate. * Age is lesser than 20 years old. * Autoimmune diseases. * Previous knee injury or infection history. * Brain region disease ex: stroke or brain tumor...etc. * Mild cognitive impairment, dementia or other neurodegenerative diseases. * Cancer. * With other chronic pain.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05570240