Central Sensitization in Total Knee Arthroplasty Patients with Persistent Pain
CompletedNCT05575310
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Persistent post-surgical pain is a significant adverse effect after total knee arthroplasty, present in around 20% of the patients. Central sensitization may contribute to developing and maintaining pain. Therefore studies should investigate if pain processing altered mechanisms are present in this population.
Study details
- Official title
- Central Sesitization in Patients with Persistent Postsurgical Pain After a Knee Arthroplasty: a Prospective, Case Control, Observational Study
- Conditions
- Pain, Chronic Postsurgical
- Knee Osteoarthritis
- Sensitization, Central
- Interventions
- Procedure: Total Knee Arthroplasty
- Sponsor
- University of Barcelona
- Collaborators
- Consorci Hospitalari de Vic; University of Vic - Central University of Catalonia
- Start date
- 2023-01-01
- Primary completion
- 2024-10-22
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Spain
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion criteria: \- Patients who underwent total knee arthroplasty due to painful primary osteoarthritis. Exclusion criteria: * Patients operated due to a revision surgery. * Patients with a unicompartmental knee arthroplasty * Pateints operated due to a fracture. * Patients planning to undergo another lower extremity operation during the following 12 months. * Patients with inflammatory or rheumatic diseases such as: rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus or ankylosing spondylitis. * Patients with mental health conditions and/or major depression.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05575310