P4ACE Trial for Persons With Chronic Knee Pain
CompletedNot applicableNCT05623683
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The goal of this single-blind, cross-over clinical trial is to compare the immediate effect of intermittent vs. continuous walking on clinical and mechanistic pain profiles in persons with knee osteoarthritis (OA). In this cross-over trial, participants will perform two types of walking on a treadmill. Intermittent walking will involve 3 blocks of 10 minutes with 2 blocks of 5-minute rest (sitting on a chair) in-between. Continuous walking will involve resting for 10 minutes (sitting in a chair) before walking on the treadmill for 1 continuous block of 30 minutes.
Study details
- Official title
- Pain Profiles and Patterns of Physical Activity in Persons With Chronic Knee Pain
- Conditions
- Interventions
- Other: Intermittent Walking
- Other: Continuous Walking
- Sponsor
- Northwestern University
- Collaborators
- Aalborg University
- Start date
- 2023-04-20
- Primary completion
- 2024-07-31
- Sex
- All
- Age range
- from 45 Years to 75 Years
- Results posted
- No results posted in this snapshot
- Countries
- Denmark
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * men or women aged 45-75 years * BMI ≤ 35 kg/m2 * frequent movement-related knee pain (knee pain on more than half the days of the past month) * no morning stiffness or morning stiffness lasting \< 30-min * self-reported unilateral or bilateral knee pain of ≥ 3 and ≤ 7 on a 0-10 numeric pain rating scale (NPRS) * knee pain duration ≥ 12 months * physically able to walk unassisted on a treadmill at ≥ 4 km/hour for 30 minutes * own a smart phone * willing and able to wear an activity monitor and answer electronic survey questions delivered via a smart phone over a 10-day period. Exclusion Criteria: * intra-articular steroid injections in the previous 3 months * intra-articular hyaluronic acid injection in the previous 6 months * any arthroscopic or surgical knee procedures (e.g., partial meniscectomy) in the past 12 months * lumbar radiculopathy * neurological, vestibular, or visual dysfunction affecting walking balance and mobility * plan for total knee arthroplasty in the next 12 months
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05623683