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Effects of Multi Radiance Medical® Super Pulsed Laser on Chronic Knee Pain

Unknown statusNot applicableNCT05830344
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

Knee pain is among the most common reasons for musculoskeletal pain consultations, accounting for nearly 4 million primary care visits annually. Knee pain can have different causes such as, tendinopathies, synovitis, bursitis, trauma, etc. Considering the importance and high incidence of musculoskeletal disorders that affect the knee joint, a variety of therapeutic modalities has been employed to alleviate pain and repair the tissue. Among these conservative treatments, photobiomodulation therapy (PBMT) has been shown to stimulate tendon and ligament healing, and decrease the pain. Therefore, the aim of this study is to determine the effectiveness of the Multi Radiance Medical® Super Pulsed Laser, manufactured by Multi Radiance Medical®, for adjunctive use in providing temporary relief of chronic knee pain of musculoskeletal origin.

Study details

Official title
Evaluation of the Effect of Multi Radiance Medical® Super Pulsed Laser for Adjunctive Use in Providing Temporary Relief of Chronic Knee Pain of Musculoskeletal Origin
Interventions
  • Device: Placebo Multi Radiance Medical® Super Pulsed Laser
  • Device: Active Multi Radiance Medical® Super Pulsed Laser
Sponsor
University of Nove de Julho
Collaborators
Multi Radiance Medical
Start date
2023-04-27
Primary completion
2023-10
Sex
All
Age range
from 18 Years to 50 Years
Results posted
No results posted in this snapshot
Countries
Brazil
Total sites listed
2

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Signed consent form. * Aged between 18 and 50 years, inclusive. * Any gender. * Subject is fluent in Portuguese. * The volunteers' presenting primary (dominant) pain is in the region of the right or left knee only. i.e., it is unilateral. * Self-reported degree of pain rating on the 0-100 VAS pain scale for the target knee is 50 or greater. * Self-reported degree of pain rating on the 0-100 VAS pain scale for the non-target knee is less than 20. * Knee pain is episodic chronic, defined as having occurred and recurred over regular or irregular periods or intervals of time, persisting over at least the last 3 months. * Volunteers' knee pain is of benign musculoskeletal origin wherein the etiology is tendinopathies, synovitis, bursitis, strain, and sprain, of traumatic or non-traumatic origin, as determined by the principal investigator based on any one or combination of the following: * Prior diagnosis by a qualified licensed medical professional current within the last 2 years evidenced through source documentation. * Previous Records Review, such as x-ray, MRI, CT scans, etc., where available, that indicate muscle or ligament injury and the absence of Degenerative Joint Disorder (DJD). * Medical history consistent with one of the etiologies of knee pain falling within the scope of this study. * Physical examination of the knee that yields one or both of the following findings: Increased pain upon range of motion and/or increased pain and weakness upon knee extension, knee flexion, or gait. * Subject is willing and able to maintain his or her individualized pain regimen as determined by the study principal investigator at baseline as needed to manage any knee pain that may arise throughout the course of study duration, whilst refraining from consuming other over the counter and/or prescription medication(s) and/or herbal supplements intended for the relief of pain and/or inflammation, and/or partaking in other treatments/therapies. Exclusion Criteria: A volunteer who satisfies any one or more of the following criteria will be excluded from study participation: * The volunteers' presenting primary pain is located outside or in addition to the knee. * The volunteers' presenting primary pain is bilateral, i.e., equally dominant in the right and left knees. * Self-reported degree of pain rating on the 0-100 VAS pain scale for the target knee is less than 50. * Self-reported degree of pain rating on the 0-100 VAS pain scale for the non-targ…

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05830344