3-point vs 6-point GNRFA for Chronic KOA
WithdrawnNot applicableNCT05930756
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Brief summary (from the registry)
The goal of this clinical trial is to compare three-point and six-point Genicular Nerve Radiofrequency Ablation (GNRFA) in adults with chronic knee osteoarthritis (KOA). The main question it aims to answer is whether six- target GNRFA technique is more efficacious than standard three-target GNRFA technique in managing the pain and function of KOA. Consented patients who respond to a diagnostic block will be randomly assigned to either three-point or six-point GNRFA. Researchers will compare pain and function in these two groups.
Study details
- Official title
- A Randomized Controlled Trial Comparing the Efficacy of a Three-Point Versus a Six-Point Genicular Nerve Radiofrequency Ablation for Chronic Knee Osteoarthritis
- Conditions
- Interventions
- Sponsor
- McMaster University
- Start date
- 2025-08-09
- Primary completion
- 2025-12-31
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Canada
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Age 18 years or older * Chronic knee pain for at least 3 months with radiological evidence of KOA graded 2-4 on the Kellgren-Lawrence scale as determined by a radiologist Exclusion Criteria: * unwilling, * unable to communicate in English, * have acute knee pain, * prior knee surgery, * allergies to local anesthetics, * chronic opioid consumption of daily morphine equivalent of \>30 mg for at least four weeks prior to procedure, * neurologic diseases affecting the lower limbs (i.e. previous CVA, MS), * connective tissue diseases affecting the knee, * treatment with intra-articular steroid injections and/or hyaluronic acid in the previous 3 months.
Canadian sites (1)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05930756