Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain
CompletedNot applicableNCT06087211
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This study aims to evaluate the effect of combined duloxetine and IV Magnesium sulphate to decrease acute and chronic post mastectomy pain. The study will be conducted in National Cancer Institute and all the participants will be enrolled from female patients scheduled for modified radical mastectomy under general anesthesia in National Cancer Institute, Cairo University.
Study details
- Official title
- Pain Relieving Potentials of Preoperative Combination of Single Dose Oral Duloxetine and Intravenous Magnesium Sulphate in Acute and Chronic Post Mastectomy Pain: A Randomized Controlled Trial
- Conditions
- Duloxetine
- Magnesium Sulphate
- Post-mastectomy Pain Syndrome
- Interventions
- Drug: Magnesium sulphate and Duloxetine
- Drug: Duloxetine
- Drug: Placebo and normal saline
- Sponsor
- National Cancer Institute, Egypt
- Start date
- 2023-10-10
- Primary completion
- 2025-01-01
- Sex
- Female
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- Egypt
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Age from 18 to 65 years old. * American Society of Anesthesiologists (ASA) physical I-II * Scheduled for modified radical mastectomy (MRM) under general anesthesia. Exclusion Criteria: * Liver or kidney disease * Patient with previous chronic pain on opioids * Patients on antidepressants and antipsychotics. * Allergies to study drugs
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06087211