Sealers in Chronic Apical Lesions
CompletedNot applicableNCT07339579
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This clinical study evaluated whether different root canal sealers influence postoperative pain and early periapical healing in patients with apical periodontitis. A total of 72 adult patients with single-rooted teeth diagnosed with chronic apical periodontitis received standardized root canal treatment and were randomly assigned to one of three commonly used sealers: AH Plus, MTA Fillapex, or Sealapex. Postoperative pain was recorded using a verbal pain rating scale immediately after treatment and at 24 and 72 hours. Periapical healing was assessed at baseline and after six months using periapical radiographs and cone-beam computed tomography (CBCT). The purpose of this study was to determine whether the type of root canal sealer affects patient comfort after treatment and the early healing of periapical tissues. Understanding these outcomes may help clinicians choose appropriate materials and better inform patients about expected pain and healing after root canal therapy.
Study details
- Official title
- Evaluation of the Effects of Root Canal Sealers on Postoperative Pain and Radiographic Healing in Patients With Apical Periodontitis
- Conditions
- Apical Periodontitis
- Postoperative Pain
- Periapical Healing
- Interventions
- Procedure: Root Canal Treatment With Sealapex
- Procedure: Root Canal Treatment With MTA Fillapex
- Procedure: Root Canal Treatment With AH Plus
- Sponsor
- Kahramanmaras Sutcu Imam University
- Start date
- 2024-01-01
- Primary completion
- 2025-06-01
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- Turkey (Türkiye)
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Adults aged 18 to 65 years * Patients diagnosed with apical periodontitis * Presence of a single-rooted anterior or premolar tooth with a radiographically visible periapical lesion * Systemically healthy individuals classified as ASA I or ASA II * Ability to understand the study procedures and provide written informed consent Exclusion Criteria: * Teeth with root fractures, external resorption, or open apices * Calcified canals or severely curved root canals (\>30°) * Periodontal pocket depth greater than 3 mm * Pregnancy * Use of antibiotics or analgesics within the previous 7 days * History of previous endodontic treatment or retreatment in the study tooth * Presence of systemic conditions that could affect healing
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07339579