Effects of Music During Walking on Pain and Muscle Activation in People With Chronic Pain Due to Knee Osteoarthritis
Not yet recruitingNot applicableNCT07537114
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this research study is to compare muscle activation, changes in pain sensitivity, and brain function, between different walking conditions, including walking to music, walking to metronome, and walking without music or metronome.
Study details
- Official title
- Effects of Music-Based Rhythmic Auditory Stimulation During Walking on Nociceptive Signaling and Muscle Activation in People With Chronic Pain Due to Knee Osteoarthritis
- Conditions
- Interventions
- Behavioral: Rhythmic Auditory Stimulation with music
- Behavioral: Rhythmic Auditory Stimulation with metronome
- Behavioral: Control
- Sponsor
- Boston University Charles River Campus
- Start date
- 2026-11
- Primary completion
- 2027-06
- Sex
- All
- Age range
- from 50 Years to 85 Years
- Results posted
- No results posted in this snapshot
- Total sites listed
- 0
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Have activity related pain * Experience morning knee stiffness ≤ 30 minutes * Knee pain on most days for 3 months or more * Able to walk at least 20 minutes with assistance * Average overall knee pain severity of ≥= 4 on a 11-point numeric rating scale during previous week * BMI ≤ 40 * Able to communicate using English at a level to understand the study procedures and informed consent Exclusion Criteria: * Contraindications to exercise * Joint replacement in either hip, knee, or ankle * History of other disease that may involve the index joint including inflammatory joint disease such as rheumatoid arthritis, seronegative spondyloarthropathy (eg, ankylosing spondylitis, psoriatic arthritis, inflammatory bowel disease related arthropathy), crystalline disease (eg, gout or pseudogout), lupus erythematosus, knee joint infections, Paget's disease affecting the knee, or knee joint tumors. * Previous knee osteotomy in either knee * Other health conditions that impact motor functioning or prevent participation (e.g., stroke, Parkinson's disease, Alzheimer's disease, Multiple Sclerosis, diabetic neuropathy, etc.) * Corticosteroid or hyaluronic acid injections in either knee in the previous 3 months * Pregnancy (self-report) * Suspected or known drugs or alcohol abuse * Mini-mental State Examination (MMSE) score \< 24 * Hearing impairments * Pain in lower back or legs that is greater than knee pain
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07537114