Erector Spinae Block Versus Paravertebral Block on Chronic Pain After Mastectomy
RecruitingNot applicableNCT07561411
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The goal of this clinical trial is to learn if the erector spinae block can reduce the incidence of chronic pain compared to the paravertebral block in adult patients undergoing total mastectomy. The study includes patients aged 18 to 80 years scheduled for mastectomy, with or without axillary dissection. The main questions it aims to answer are: * Does erector spinae block reduce the incidence of chronic pain at 3 months after mastectomy compared to paravertebral block? * Does erector spinae block affect postoperative outcomes such as opioid consumption at 48 hours, pain scores (in PACU, 24 and 48 hours), block performance time, and the incidence of complications, anxiety or depression, and pain intensity at 3 months? Researchers will compare patients receiving erector spinae block to those receiving paravertebral block to determine if erector spinae block provides equivalent or improved outcomes in terms of chronic pain and perioperative measures. Participants will: * Be randomly assigned to receive either erector spinae block or paravertebral block prior to surgery * Undergo total mastectomy (with or without axillary dissection) * Have their pain assessed in the PACU and at 24 and 48 hours postoperatively * Have opioid consumption measured during the first 48 hours after surgery * Be followed up at 3 months to assess chronic pain, pain intensity, and psychological outcomes (anxiety or depression)
Study details
- Official title
- The Effect of Erector Spinae Block Versus Paravertebral Block on the Incidence of Chronic Pain After Mastectomy: A Randomized Controlled Trial
- Conditions
- Mastectomy
- Lymphedema
- Chronic Pain
- Regional Anesthesia Morbidity
- Opioid Use
- Interventions
- Drug: Paravertebral block
- Drug: Erector Spinae block
- Sponsor
- American University of Beirut Medical Center
- Start date
- 2026-05-19
- Primary completion
- 2028-05-01
- Sex
- All
- Age range
- from 18 Years to 80 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Lebanon
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Adult patients between 18 and 80 years old. * Scheduled to total mastectomy with or without axillary dissection * Willing to receive regional anesthesia in addition to GA * ASA classification 1-3 Exclusion Criteria: * Previous thoracic surgery with an incision of \>2 cm * Patient's refusal * Allergy to local anesthetics * Pregnant women * Any contraindications to thoracic PVB, including intrathoracic infection, infection at the puncture site, cancer invasion of the puncture site, severe spinal deformity, history of spinal surgery, and severe coagulopathy; anticoagulants intake. * American Society of Anesthesiologists (ASA) classification of 4 or higher, * History of chronic pain or untreated clinical severe depression
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07561411