Effects of Physiotherapy on Ultrasound and Clinical Parameters in Women With Dysmenorrhea
Not yet recruitingNot applicableNCT07645196
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Dysmenorrhea affects up to 90% of women of reproductive age and represents a significant public health concern. Beyond prostaglandin-mediated uterine contractions, dysmenorrhea involves central sensitization mechanisms and myofascial components, including abdominal trigger points. Despite growing interest in physiotherapy for chronic pelvic pain, objective data on tissue-level changes induced by manual therapy remain scarce. This randomized single-blind sham-controlled trial aims to evaluate the effects of abdominal manual mobilization techniques on (1) tissue stiffness measured by shear wave elastography at the uterine cervix and bilateral abdominal regions, and (2) clinical outcomes including pain intensity and quality of life in women with dysmenorrhea, with or without endometriosis. Participants will be randomly assigned to either a treatment group receiving standardized abdominal manual therapy or a sham group receiving superficial manual contact. Assessments will be conducted over three menstrual cycles using shear wave elastography, the Numeric Rating Scale (NRS), and the SF-36 questionnaire.
Study details
- Official title
- Effects of Physiotherapy on Ultrasound and Clinical Parameters in Women With Dysmenorrhea With or Without Endometriosis
- Conditions
- Dysmenorrhea
- Endometriosis
- Interventions
- Procedure: Abdominal manual mobilization
- Procedure: Sham manual contact
- Sponsor
- Vrije Universiteit Brussel
- Start date
- 2026-09
- Primary completion
- 2028-09
- Sex
- Female
- Age range
- from 18 Years to 50 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Belgium
- Total sites listed
- 2
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * female sex * aged 18 to 50 years * clinical diagnosis of dysmenorrhea (cyclic pelvic pain during menstruation) Exclusion Criteria: * Pregnancy or breastfeeding * Delivery less than 1 year prior to enrollment * History of abdominal or pelvic surgery within the past 3 months * Diagnosis of fibromyalgia, diabetes, or cancer * Ongoing manual therapy treatment of the abdominal or genital area
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07645196