Sickle Cell Disease: clinical trials and information
Sickle Cell Disease clinical trials in Canada
No registry record in this snapshot uses this exact term with a site in Canada. See related conditions below.
Sickle Cell Disease clinical trials worldwide (outside Canada)
24 trials, 5 recruiting or not yet recruiting. Recruiting first.
| Phase | Countries | ||||
|---|---|---|---|---|---|
| MBI for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease NCT07797582 | Not yet recruiting | Not applicable | University of Illinois at Chicago | 2027-02 | |
| Cannabinoids for the Reduction of Inflammation and Sickle Cell Related Pain NCT05519111 | Recruiting | Phase 2 | United States | Icahn School of Medicine at Mount Sinai | 2025-04-03 |
| Cannabidiol in Sickle Cell Disease NCT06930703 | Recruiting | Phase 1, Phase 2 | United States | Icahn School of Medicine at Mount Sinai | 2025-04-03 |
| Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease NCT07001631 | Recruiting | Not applicable | Netherlands | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2024-09-20 |
| Predictors of Pain in Sickle Cell Disease NCT06139510 | Recruiting | Not applicable | United States | Duke University | 2024-07-12 |
| Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease NCT07402811 | Completed | Not applicable | United States | University of Illinois at Chicago | 2025-12-06 |
| Sickle Cell, Pain and Mediterranean Diet NCT06886477 | Completed | Not applicable | United States | University of Illinois at Chicago | 2025-05-01 |
| Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD) NCT05457790 | Suspended | Not applicable | United States | National Cancer Institute (NCI) | 2024-05-03 |
| The Living With a Long-Term Condition Study NCT06072287 | Unknown status | United Kingdom | King's College London | 2023-06-28 | |
| Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease Pain NCT04906447 | Completed | Phase 2 | United States | University of Illinois at Chicago | 2021-11-24 |
| Home-Based Intervention for Chronic Pain in Adults With Sickle Cell Disease NCT04906707 | Completed | Not applicable | United States | Emory University | 2021-10-27 |
| Building Adaptive Coping and Knowledge to Improve Daily Life NCT04602728 | Completed | Not applicable | United States | Emory University | 2021-01-27 |
| Imatinib for Pain in Sickle Cell Anemia NCT03997903 | Terminated | Phase 1, Phase 2 | United States | Indiana University | 2020-02-26 |
| Acupuncture for Adults With Sickle Cell Disease (SCD): A Feasibility Study NCT04156399 | Terminated | Not applicable | United States | University of Illinois at Chicago | 2020-01-15 |
| Outcomes Mandate National Integration With Cannabis as Medicine NCT03944447 | Unknown status | Phase 2 | United States | OMNI Medical Services, LLC | 2018-12-01 |
| Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease NCT03694548 | Terminated | Not applicable | United States | Emory University | 2018-11-08 |
| MUSic Therapy to Improve Quality Of Life in Sickle Cell Disease (MUSIQOLS) NCT03556657 | Completed | Not applicable | United States | University Hospitals Cleveland Medical Center | 2018-08-27 |
| Computerized Cognitive Behavioral Therapy Assisted Life Management for Pain in Sickle Cell Disease NCT03029468 | Completed | Not applicable | United States | University of Pittsburgh | 2018-03-28 |
| Distracting Through Procedural Pain and Distress NCT04892160 | Completed | Not applicable | United States | Medical College of Wisconsin | 2018-02-15 |
| Vaporized Cannabis for Chronic Pain Associated With Sickle Cell Disease NCT01771731 | Completed | Phase 1, Phase 2 | United States | University of California, San Francisco | 2014-08 |
| Validating Pain Scales in Children and Young Adults NCT01639950 | Completed | United States | National Cancer Institute (NCI) | 2012-08-06 | |
| Use of a Mobile-based App for SCD Patients NCT01833702 | Completed | United States | Duke University | 2012-06 | |
| High Dose Vitamin D for Sickle Cell Disease NCT01331148 | Completed | Phase 2 | United States | Wake Forest University Health Sciences | 2009-02 |
| Home Based Massage and Relaxation for Sickle Cell Pain NCT00066079 | Completed | Phase 2 | United States | National Center for Complementary and Integrative Health (NCCIH) | 2003-08 |
About Sickle Cell Disease
What is Sickle Cell Disease?
"Sickle Cell Disease" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 24 chronic pain registry records worldwide.
How is Sickle Cell Disease usually assessed?
Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.
What kinds of treatments are studied for Sickle Cell Disease?
Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.
How can I find Sickle Cell Disease clinical trials in Canada?
No registry record in this snapshot uses this exact term with a site in Canada. Related terms are linked below. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.
Related interventions
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.