Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain
CompletedPhase 4NCT02527083
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Research suggests that the type of anesthesia used for surgery may affect intraoperative stress hormone levels. There is also data to support that an increased level of stress hormones leads to increased pain after surgery. The primary aim of this study is to determine the effect of anesthesia type on long term pain after hernia surgery. In this study, patients undergoing inguinal hernia repair will be randomized to an anesthetic group, either Total Intravenous Anesthesia (TIVA) maintained with propofol or Balanced Inhaled Anesthesia (BIA) maintained with sevoflurane. This will allow us to look at any differences in short and long-term pain after hernia repair depending on type of anesthesia received.
Study details
- Official title
- Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain
- Conditions
- Acute Pain
- Chronic Pain
- Hernia
- Anesthesia, Intravenous
- Anesthesia, Intratracheal
- Sponsor
- VA Pittsburgh Healthcare System
- Start date
- 2015-01
- Primary completion
- 2019-06
- Sex
- Male
- Age range
- from 18 Years
- Results posted
- Yes, on ClinicalTrials.gov
- Total sites listed
- 0
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * All male patients undergoing herniorrhaphy surgery that requires general anesthesia. Exclusion Criteria: * Subjects unable to communicate directly with the investigators, due to being non-English speaking, loss of hearing, or incompetence. * A history of malignant hyperthermia, pseudocholinesterase deficiency, or other disease that prevents anesthetic randomization. * Pain-related disorders such as fibromyalgia or other chronic pain syndromes. * Emergency surgery.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02527083