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Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain

CompletedPhase 4NCT03280017
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

Postoperative pain after thoracic surgery is associated with adverse outcomes. The current strategy to prevent postoperative pain is the use of regional anesthesia and analgesic agents. In video-assisted thoracic surgery (VATS), thoracic paravertebral block has become the standard analgesic regimen which results in decreased postoperative pain and opioid consumption. The investigator would like to study the analgesic efficacy of low dose intravenous ketamine infusion during surgery in combination with thoracic paravertebral block on postoperative pain after VATS in a randomized study.

Study details

Official title
Low Dose Intraoperative Intravenous Ketamine in Combination With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain: a Randomized Study
Sponsor
Mahidol University
Start date
2017-09-25
Primary completion
2018-12-31
Sex
All
Age range
from 18 Years to 70 Years
Results posted
No results posted in this snapshot
Countries
Thailand
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * American Society of Anesthesiologist physical status 1-3 * Scheduled for elective video-assisted thoracic surgery * Able to operate a patient-controlled analgesia device (PCA) Exclusion Criteria: * History of morphine allergy * History of bupivacaine allergy * Contraindication for ketamine infusion * Contraindication for thoracic paravertebral block * Anticipated postoperative positive pressure ventilation * Body mass index more than 35 * Any known psychiatric disorder

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03280017