Pain, Acute: clinical trials and information
"Pain, Acute" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 52 chronic pain registry records worldwide.
4
Trials with Canadian sites
1
Recruiting in Canada
52
Registry records worldwide
Pain, Acute clinical trials in Canada
4 trials, recruiting first
| Phase | Provinces | ||||
|---|---|---|---|---|---|
| UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture NCT05865327 | Recruiting | Not applicable | Ontario | Sunnybrook Health Sciences Centre | 2023-10-23 |
| Online Psychology Program for Chronic Pain After Surgery NCT06455345 | Completed | Not applicable | Ontario | University Health Network, Toronto | 2024-01-20 |
| Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial NCT04274530 | Completed | Not applicable | Alberta, Newfoundland and Labrador, Ontario | McMaster University | 2021-01-25 |
| Pawsitive Impacts of Therapy Dog Visits NCT04727749 | Completed | Not applicable | Saskatchewan | University of Saskatchewan | 2019-06-07 |
Pain, Acute clinical trials worldwide (outside Canada)
48 trials, 5 recruiting or not yet recruiting. Recruiting first.
| Phase | Countries | ||||
|---|---|---|---|---|---|
| Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients NCT07144033 | Not yet recruiting | Not applicable | Hong Kong | Chinese University of Hong Kong | 2026-01-01 |
| Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA) NCT06604507 | Not yet recruiting | Ukraine | Winfried Meißner | 2024-10-15 | |
| Affecting Factors for Chronic Pain After Sternotomy NCT06534372 | Recruiting | Turkey (Türkiye) | Ankara Etlik City Hospital | 2024-09-01 | |
| Stellate Ganglion Block for Prevention of Post Mastectomy Depression NCT06263907 | Recruiting | Not applicable | Egypt | Mansoura University | 2024-03-01 |
| fMRI and IVCM Cornea Microscopy of CXL in Keratoconus NCT04439552 | Recruiting | United States | Boston Children's Hospital | 2021-10-04 | |
| Affecting Factors for Chronic Pain After Mastectomy NCT06592053 | Completed | Turkey (Türkiye) | Ankara Etlik City Hospital | 2024-09-25 | |
| Methadone Pharmacokinetics in End-stage Renal Disease NCT06056245 | Unknown status | Chile | Pontificia Universidad Catolica de Chile | 2024-04-05 | |
| Lumbar ESPB in Hip Replacement Surgery NCT06282666 | Completed | Not applicable | Poland | Medical University of Lublin | 2024-02-19 |
| Intravenous Methadone in Perioperative Acute and Chronic Management in Chinese Adult Cardiac Surgical Patients NCT05913284 | Active, not recruiting | Phase 3 | Hong Kong | Chinese University of Hong Kong | 2024-01-15 |
| Prevalence of Pain in Hospitalized Cirrhotic Patients NCT06062108 | Completed | France | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | 2023-11-10 | |
| Dexmedetomidine and Morphine as Adjuvants to US Guided Erector Spinae Plane Blocks in Elective Thoracic Surgeries NCT05843344 | Unknown status | Not applicable | Greece | Dr Kassiani Theodoraki | 2023-05-01 |
| Evaluation of the Effect of a Food Supplement Based on Hydrolyzed Collagen on Joint Function. NCT05917925 | Unknown status | Not applicable | Spain | Francisco Javier Martínez Noguera | 2023-04-01 |
| Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery NCT04718116 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2022-11-01 |
| Opioid Sparing Anesthesia in Cervical Spine Surgery NCT05717361 | Unknown status | Not applicable | Greece | Evangelismos Hospital | 2022-11-01 |
| The Impact of Esmolol Administration on Postoperative Recovery NCT05567822 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2022-10-01 |
| VR Mindfulness Study NCT05592782 | Withdrawn | Not applicable | University of California, Los Angeles | 2022-10 | |
| PROCO Neck: The Course and Neuroplasticity in Neck Pain-Associated Disorders and Whiplash-Associated Disorders NCT05468684 | Unknown status | Switzerland | University of applied sciences | 2022-09-01 | |
| Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function NCT05886608 | Completed | Not applicable | Italy | Contrad Swiss SA | 2022-08-30 |
| Opioid Sparing Anesthesia in Lumbar Spine Surgery NCT05594407 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2022-08-01 |
| The Adolescent Surgery Experience: A Mixed Methods Analysis NCT05482919 | Completed | United States | Children's Hospital of Philadelphia | 2022-06-14 | |
| Opioid-free Anesthesia in Thyroidectomies NCT05243940 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2022-03-07 |
| Effect of Ultrasound Guided Thoracic Interfascial Plane Block Versus Erector Spinae Plane Block After Mastectomy NCT05176938 | Unknown status | Not applicable | Tanta University | 2022-01-10 | |
| Opioid-free Anesthesia in Laparoscopic Cholecystectomies NCT05089526 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2021-10-11 |
| Pharmacist-led Pharmacogenomic Clinical Service Within the Program of All-inclusive Care for the Elderly NCT04971902 | Unknown status | United States | Tabula Rasa HealthCare | 2021-07-01 | |
| Online Mindfulness-based Intervention to Prevent Chronic Pain NCT04848428 | Completed | Not applicable | United States | Florida State University | 2021-05-01 |
| Morphine Versus Ketamine as Adjuvants in Paravertebral Blocks NCT04852484 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2021-04-16 |
| Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine NCT04858711 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2021-04-01 |
| Use of Virtual Reality in Pain Management in Hospitalized Patients NCT05545033 | Completed | Not applicable | Singapore | Changi General Hospital | 2021-01-20 |
| Lidocaine and Magnesium and Ketamine in Gynecological Surgery NCT04622904 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2020-11-14 |
| Changes in Affective Pain Processing in Human Volunteers NCT04280796 | Completed | Not applicable | Switzerland | susanne becker | 2020-09-21 |
| Real-World Experience of Patients Treated for Musculoskeletal Injuries With SAM in Routine Care NCT05254470 | Completed | United States | ZetrOZ, Inc. | 2020-09-01 | |
| The Effect of Palmitylethanolamide on Central and Peripheral Sensitization After Heat-induced Hyperalgesia NCT04662827 | Completed | Not applicable | Austria | Medical University of Graz | 2020-02-09 |
| Double-blind, Placebo-control, Study to Evaluate the Safety and Pharmacokinetics of CT-044 HCl, in Healthy Volunteers NCT04175743 | Unknown status | Phase 1 | United States | Lotus Clinical Research, LLC | 2019-12-04 |
| Is it Necessary to Fix Mesh in Laparoscopic Hernia Repair NCT05152654 | Completed | Not applicable | Turkey (Türkiye) | Hitit University | 2019-12-01 |
| Nutraceuticals and Functional Foods NCT05509075 | Unknown status | Italy | University of Catanzaro | 2019-11-12 | |
| Ketamine to Improve Recovery After Cesarean Delivery - Part 1 NCT04037085 | Completed | Phase 2 | United States | Grace Lim, MD, MS | 2019-10-09 |
| Assessing Opioid Care Practices Using CPV Patient Simulation Modules NCT04080037 | Completed | Not applicable | United States | Qure Healthcare, LLC | 2019-09-03 |
| The Impact of Music on Nociceptive Processing NCT04087564 | Completed | Not applicable | United States | Brigham and Women's Hospital | 2019-06-13 |
| Noninvasive Brain Stimulation for Pain Relief NCT04283643 | Unknown status | Not applicable | United States | University of Virginia | 2019-04-01 |
| Qualitative Study for Pain Measurement Using Innovative Health Technology NCT03727373 | Completed | Germany | University Hospital Schleswig-Holstein | 2018-10-17 | |
| EHR Precision Drug Treatment in Neonates NCT04850079 | Unknown status | United States | Children's Hospital Medical Center, Cincinnati | 2018-09-28 | |
| Utility of an APP for the Monitoring of Irruptive Oncological Pain NCT03597737 | Completed | Not applicable | Spain | Universitat Jaume I | 2018-08-10 |
| Development and Validation of a Digital Pain-Reduction Kit for Musculoskeletal Injuries NCT03187132 | Completed | Not applicable | United States | Cedars-Sinai Medical Center | 2018-04-03 |
| Dexmedetomidine in TAP Block for Inguinal Hernia Repair NCT04403711 | Completed | Not applicable | Greece | Aretaieion University Hospital | 2018-04-01 |
| Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty NCT03271151 | Completed | Phase 4 | United States | Hospital for Special Surgery, New York | 2017-09-28 |
| Interscalene Block Versus Superior Trunk Block NCT03272139 | Completed | Phase 4 | United States | Hospital for Special Surgery, New York | 2017-09-28 |
| Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain NCT03280017 | Completed | Phase 4 | Thailand | Mahidol University | 2017-09-25 |
| Real-World Experience of Athletes Treated With SAM NCT04177537 | Completed | ZetrOZ, Inc. | 2015-10-01 |
About Pain, Acute
What is Pain, Acute?
"Pain, Acute" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 52 chronic pain registry records worldwide.
How is Pain, Acute usually assessed?
Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.
What kinds of treatments are studied for Pain, Acute?
Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.
How can I find Pain, Acute clinical trials in Canada?
This page lists 4 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.
Related interventions
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.