Duloxetine vs Pregabalin for Thoracotomy Pain
Unknown statusPhase 4NCT04782310
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This study investigates the effects of preoperative use of oral combination of duloxetine and Pregabalin in comparison with preoperative oral Pregabalin only in treatment of acute postoperative and prevention of chronic pain following thoracotomy surgeries.
Study details
- Official title
- Effectiveness of Adding Duloxetine to Pregabalin in Treatment of Acute Postoperative and Prevention of Chronic Pain Following Thoracotomy Surgeries; Randomized Controlled Study
- Conditions
- Interventions
- Sponsor
- Cairo University
- Start date
- 2021-03-10
- Primary completion
- 2021-08-10
- Sex
- All
- Age range
- from 18 Years to 60 Years
- Results posted
- No results posted in this snapshot
- Countries
- Egypt
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * ● Physical status ASA II, III. * Age ≥ 18 and ≤ 65 Years. * Body mass index (BMI): \> 20 kg/m2 and \< 40 kg/m2. * Cancer patients undergoing posterolateral thoracotomy incision for cancer lung, mesothelioma or metastatectomy from the lung. * Patient is able to provide a written informed consent. Exclusion Criteria: * ● Patients with Known sensitivity or contraindication to drug used in the study * History of psychological disorders and/or chronic pain. * Previous administration of antidepressants, anticonvulsants, or opioids before surgery. * Patient refusal. * Severe respiratory or cardiac disorders. * Advanced liver or kidney disease.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04782310