Morphine Versus Ketamine as Adjuvants in Paravertebral Blocks

Unknown statusNot applicableNCT04852484

View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

The aim of this study will be to compare the effects of morphine versus ketamine when they are used as adjuvants to the local anesthetic in paravertebral nerve blocks performed with the aid of ultrasound. Furthermore, a group of local anesthetic without an adjuvant, will also be compared to the two groups

Study details

Official title: Morphine Versus Ketamine as Adjuvants in Ultrasound-guided Paravertebral Thoracic Blocks in Elective Thoracic Surgery
Conditions: Pain, Postoperative
Pain, Acute
Pain, Chronic
Pain, Neuropathic
Morphine
Ketamine
Analgesia
Interventions: Drug: local anesthetic-morphine
Drug: local anesthetic-ketamine
Drug: local anesthetic
Sponsor: Aretaieion University Hospital
Collaborators: KAT General Hospital
Start date: 2021-04-16
Primary completion: 2024-04-16
Sex: All
Age range: from 25 Years to 80 Years
Results posted: No results posted in this snapshot
Countries: Greece
Total sites listed: 2

Eligibility criteria

Show eligibility criteria (verbatim from the registry)

Inclusion Criteria: * patients undergoing elective thoracotomy for any cause * American Society of Anesthesiologists class I-III (ASA I-III) Exclusion Criteria: * known allergy to local anesthetic * local inflammation * paravertebral tumor * severe respiratory distress ( breathing dependence on accessory muscles) * severe spinal deformities * severe ipsilateral diaphragmatic paresis * morbid obesity (BMI\>35 kg/m2) * blood coagulation disorders * known contraindication for administration of ketamine or morphine * psychiatric disorders * severe cardiovascular disease * systematic use of opioids due to chronic pain * renal or hepatic failure * patients who refuse to participate

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04852484