Opioid Sparing Anesthesia in Lumbar Spine Surgery
Unknown statusNot applicableNCT05594407
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus remifentanil analgesia in lumbar spine surgery
Study details
- Official title
- The Effect of a Regimen of Opioid Sparing Anesthesia on Postoperative Recovery
- Conditions
- Pain, Postoperative
- Pain, Acute
- Pain, Chronic
- Pain, Nociceptive
- Ketamine
- Lidocaine
- Dexmedetomidine
- Analgesia
- Analgesics
- Lumbar Spine Surgery
- Interventions
- Drug: dexmedetomidine-ketamine-lidocaine
- Drug: Remifentanil
- Sponsor
- Aretaieion University Hospital
- Start date
- 2022-08-01
- Primary completion
- 2024-08-01
- Sex
- All
- Age range
- from 18 Years to 75 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Greece
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Adult patents * American Society of Anesthesiologists (ASA) class I-III * elective spine surgery Exclusion Criteria: * body mass index (BMI) \>35 kg/m2 * contraindications to local anesthetic administration * systematic use of analgesic agents preoperatively * chronic pain syndromes preoperatively * neurological or psychiatric disease on treatment * pregnancy * severe hepatic or renal disease * history of cardiovascular diseases/ arrhythmias/ conduction abnormalities * bradycardia(\<55 beats/minute) * drug or alcohol abuse * language or communication barriers lack of informed consent
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05594407