Genicular Embolization Using Doxycycline Sclerotherapy

WithdrawnPhase 2NCT07024654

View the official record on ClinicalTrials.gov

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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

The goal of this prospective case series is to develop an alternative pain management procedure for patients who are not surgical candidates. The main question it aims to answer is: Is genicular sclerotherapy using doxycycline a safe and effective pain management option for patients with chronic knee pain who are not surgical candidates? OUTCOME MEASURES: Primary: Visual Analog Scale (VAS) score at 3 months Secondary: * VAS at 12 months * Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score at 12 months

Study details

Official title: A Prospective Case Series: Genicular Embolization Using Doxycycline Sclerotherapy
Conditions: Chronic Knee Pain
Osteoarthritis
Interventions: Drug: Doxycycline Injection
Sponsor: Campbell Clinic
Start date: 2026-06
Primary completion: 2027-06
Sex: All
Age range: from 18 Years
Results posted: No results posted in this snapshot
Total sites listed: 0

Eligibility criteria

Show eligibility criteria (verbatim from the registry)

Inclusion Criteria: * At least 18 years of age or older. * KL Score 2-3 * VA Grade \>5 * Native knee * Willing and able to provide consent. * Willing and able to complete questionnaires. * Willing and able to complete follow up visits. * Speak and write fluent English * Unilateral knee (if bilateral knee pain, identify knee for procedure) * All subjects may be included regardless of sex. Women must be either surgically sterilized postmenopausal defined as having no menstrual periods for 12 consecutive months Exclusion Criteria: * Allergies to doxycycline or any other substances used in procedure * Steroid injection in the index knee within the last 90 days * Knee surgery on index knee in the last 180 days

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07024654