Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery
Not yet recruitingNot applicableNCT07197684
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The goal of this clinical trial is to is to compare the effectiveness of ultrasound-guided Pecs block with intravenous ketamine versus intravenous ketamine infusion alone in preventing Chronic Post-Surgical Pain (CPSP) in patients undergoing breast cancer surgery. The main question it aims to answer is, How effective is the ketamine and ketamine with pecs block in reducing the frequency of Chronic Post-Surgical Pain after breast cancer surgery
Study details
- Official title
- Effect of Ultrasound Guided Pecs Block With Intravenous Ketamine and Ketamine Infusion Alone For Prevention of Chronic Post-Surgical Pain in Patients Undergoing Breast Cancer Surgery: A Randomized Controlled Trial
- Conditions
- Breast Cancer
- Pain, Chronic
- Post Surgical Pain
- Interventions
- Drug: Ketamine
- Procedure: Pecs block
- Drug: Nalbuphine
- Drug: Paracetamol
- Sponsor
- Aga Khan University
- Start date
- 2026-03-16
- Primary completion
- 2026-12-01
- Sex
- Female
- Age range
- from 18 Years to 75 Years
- Results posted
- No results posted in this snapshot
- Total sites listed
- 0
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Adult female patients with breast cancer aged between 18-75 years * ASA (American Society of Anesthesia) physical status I, II, and III * Patients scheduled for elective breast cancer surgery (Mastectomy with or without axillary clearance) Exclusion Criteria: * Refusal to participate or withdrawal of informed consent * Surgical procedures involving breast reconstruction with flaps or implants * Patient scheduled for bilateral mastectomy * Reoperation on the same side due to cancer recurrence * Known allergy or contraindication to study drugs * History of severe psychiatric illness (e.g., major depression, bipolar disorder, schizophrenia) * Chronic opioid use, substance abuse, or opioid addiction * Pre-existing chronic pain or neuropathic pain disorders * Coagulopathy, anticoagulation therapy, or localized infection at the site of block * Uncontrolled hypertension and ischemic heart disease
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07197684