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Chronic Low-back Pain (cLBP): clinical trials and information

Chronic low back pain is back pain that lasts for 12 weeks or longer. In many cases no single specific cause is found. It is one of the most common reasons people see a health professional.
1
Trials with Canadian sites
1
Recruiting in Canada
36
Registry records worldwide

Chronic Low-back Pain (cLBP) clinical trials in Canada

1 trial, recruiting first
PhaseProvinces
Combining Brain Stimulation and Physiotherapy for the Management of Chronic Low Back Pain
NCT06999772
RecruitingNot applicableQuebecLaval University2025-06-11

Chronic Low-back Pain (cLBP) clinical trials worldwide (outside Canada)

35 trials, 18 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Exercise-Based Strategies for Chronic Back Pain
NCT07475481
Not yet recruitingNot applicableCzechiaCharles University, Czech Republic2027-07-01
Pain Science Education and Graded Exposure for Chronic Low Back Pain
NCT07836946
Not yet recruitingNot applicableUniversity of Chile2026-11-02
TECAR Therapy in Chronic Back Pain
NCT07821021
Not yet recruitingNot applicableUniversity of Hartford2026-10-19
Impact of the Receptive Music Intervention Tool (MUSIC CARE©) on Changes in the Functional Abilities of Patients With Chronic Low Back Pain
NCT07731204
Not yet recruitingNot applicableFranceLNA SANTE2026-10-01
Virtual Tai Chi for Chronic Low Back Pain (Spine 2027)
NCT07772154
Not yet recruitingNot applicableUnited StatesNew York Medical College2026-10-01
Comparing Non-Medicine Strategies for Improving Low Back Pain
NCT07679178
Not yet recruitingNot applicableUnited StatesDuke University2026-10
Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling
NCT07846163
RecruitingGreeceAristotle University Of Thessaloniki2026-09-07
Combined and Aquatic Exercise in Chronic Low Back Pain
NCT07732595
Not yet recruitingNot applicablePortugalUniversity of Beira Interior2026-09
Effects Of Vacuum Controlled Static Versus Vacuum Controlled Dynamic Dry Cupping On Pain, Range Of Motion And Disability Among Patients With Chronic Low Back Pain
NCT07702617
Not yet recruitingNot applicablePakistanLahore University of Biological and Applied Sciences2026-07-01
Imaging Metabolic and Perfusion Changes in Acupuncture Therapy for Myofascial Pain Syndrome
NCT07494162
RecruitingNot applicableUnited StatesUniversity of California, Davis2026-05-18
Treatment Validation for Myofascial Pain
NCT07133139
RecruitingNot applicableUnited StatesAjay Wasan, MD, Msc2025-10-06
Effects of PEMM in Chronic Low Back Pain Women With Urinary Incontinence
NCT07351851
RecruitingNot applicableQatarHamad Medical Corporation2025-09-29
Acceptance and Commitment Therapy Plus Exercise for Older People With Chronic Low-back Pain: A Pragmatic Cluster Randomised Controlled Trial
NCT07211464
RecruitingNot applicableHong KongThe Hong Kong Polytechnic University2025-09-01
Effects of a Hip Flexor and Extensor Muscle Training Program in Individuals with Chronic Mechanical Low Back Pain
NCT06787209
Not yet recruitingNot applicableSpainLucía Pilar Vicente Pina2025-03
Effectiveness of a Multidisciplinary Treatment for Patients With Chronic Low Back Pain
NCT06679205
RecruitingNot applicableSpainUniversity of Barcelona2025-01-14
Pain Phenotypes in Individuals With Chronic Low Back Pain
NCT07766200
RecruitingTurkey (Türkiye)Kutahya Health Sciences University2025-01-02
The Relationship Between Disability, Fear Avoidance Beliefs, Physical Performance and Quality of Life in Chronic Low Back Pain
NCT06869668
RecruitingTurkey (Türkiye)Istanbul Arel University2024-11-30
Brain Mechanisms Supporting Cannabis-induced Pain Relief
NCT04982965
RecruitingEarly phase 1United StatesUniversity of California, San Diego2021-05-07
Virtual Reality Based High-intensity Interval Training in Chronic Low Back Pain
NCT07388134
CompletedNot applicableSpainUniversidad de Granada2026-02-09
Effects of Vertebral Axial Loading Walking Combined With Core Stabilization Exercises in Individuals With Chronic Low Back Pain
NCT07334782
Active, not recruitingNot applicableTurkey (Türkiye)Hacettepe University2026-01-19
Biopsychosocial Model-based Care Versus Routine Physical Therapy in Chronic Back Pain
NCT07280806
CompletedNot applicablePakistanLahore University of Biological and Applied Sciences2025-11-04
Clinical Research of Effectiveness and Safety of Herbal Medicine Strategy for Chronic Low Back Pain
NCT07058376
Enrolling by invitationNot applicableSouth KoreaJaseng Medical Foundation2025-10-31
Melatonin for Patients With Chronic Low Back Pain
NCT06859957
Active, not recruitingPhase 3NetherlandsBart Koes2025-04-11
Yoga and Mindfulness for Chronic Low Back Pain: A Randomized Controlled Trial
NCT06910982
Enrolling by invitationNot applicablePakistanUniversity of Karachi2025-04-01
Therapeutic Exercise Plus Pain Neuroscience Education for Chronic Low Back Pain
NCT07856992
CompletedNot applicableChinaQingdao Municipal Hospital2025-01-06
Visual Feedback Manipulation in Virtual Reality Alters Extension-evoked Pain Perception in Chronic LBP
NCT06750900
CompletedSpainCardenal Herrera University2024-12-04
Factors Associated With Quality of Life in Chronic Low Back Pain
NCT06694493
CompletedTurkey (Türkiye)Kutahya Health Sciences University2024-11-29
Dry Needling Versus Cyriax Technique on Pain, Paraesthesia and Functional Disability in Patients With Chronic Low Back Pain
NCT07089472
CompletedNot applicablePakistanUniversity of Lahore2024-11-25
Effects of a Land and Aquatic Exercise-based Program on Pain, Mobility and Quality of Life in Patients With Chronic Low Back Pain
NCT06641570
CompletedNot applicablePortugalInstituto Politécnico de Leiria2024-09-30
Investigation of Conservative Treatment Preferences of Patients With Chronic Low Back and Neck Pain
NCT06898502
CompletedNot applicableTurkey (Türkiye)Istanbul University - Cerrahpasa2024-09-01
Core Muscle Training in Patients With Chronic Mechanical Low Back Pain
NCT07448766
CompletedNot applicableEgyptCairo University2024-09-01
Static Core Stability vs. Extension Exercises for Chronic Low Back Pain
NCT06751173
CompletedNot applicablePakistanRiphah International University2024-07-15
The Effect Of Kinesiotape Application In Chronic Low Back Pain
NCT06684145
CompletedNot applicableTurkey (Türkiye)Firat University2024-03-10
Effectiveness of Radial Extracorporeal Shockwave Therapy in Patients With Chronic Low Back Pain
NCT05308641
Active, not recruitingNot applicableGermanyRuhr University of Bochum2022-09-18
Mindfulness-Based Therapy for Chronic Low Back Pain in Office Workers
NCT07621302
CompletedNot applicableTurkey (Türkiye)Dokuz Eylul University2022-04-04

About Chronic Low-back Pain (cLBP)

What is Chronic Low-back Pain (cLBP)?

Chronic low back pain is back pain that lasts for 12 weeks or longer. In many cases no single specific cause is found. It is one of the most common reasons people see a health professional.

How is Chronic Low-back Pain (cLBP) usually assessed?

Assessment usually involves a history and physical examination, with attention to warning signs that may need urgent investigation. Imaging is not needed in every case; clinicians decide based on symptoms and findings.

What kinds of treatments are studied for Chronic Low-back Pain (cLBP)?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Chronic Low-back Pain (cLBP) clinical trials in Canada?

This page lists 1 registry record for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related conditions

Related interventions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.