| RE-SCALE: Rehabilitation Engagement and Scaled Access With eXtended Reality and Artificial Intelligence NCT07202975 | Not yet recruiting | Not applicable | | Universitat Jaume I | 2027-01-01 |
| Empowering Pain Psychology Access and Collaboration (EPPAC) to Improve Treatment Engagement Among Medicaid-insured Adults With Chronic Low Back Pain NCT07843706 | Not yet recruiting | Not applicable | United States | Johns Hopkins University | 2026-11-02 |
| Magnetic Resonance Elastography Of Chronic Low Back Pain Before And After Therapy NCT07712458 | Not yet recruiting | Not applicable | United States | Mayo Clinic | 2026-11-01 |
| Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain NCT07306364 | Not yet recruiting | Phase 2 | United States | Yale University | 2026-10 |
| SENECA - Smart Therapies for Chronic Pain NCT07628179 | Not yet recruiting | Not applicable | Austria | Aurimod GmbH | 2026-09-17 |
| Integration of Virtual Reality and Traditional Acupuncture: From Education to Clinical Practice. NCT07816796 | Not yet recruiting | Not applicable | | China Medical University Hospital | 2026-09-08 |
| Study of Correlation Between Serum BDNF Levels and Pfirmann Grading and IL- 1β NCT07807839 | Recruiting | | South Korea | Keimyung University Dongsan Medical Center | 2026-09-01 |
| Spinery Basivertebral Nerve Ablation for Vertebrogenic Chronic Low Back Pain NCT07696507 | Not yet recruiting | Not applicable | Italy | Axon srl | 2026-09 |
| Biologic Injection For Adults With Lumbar Disc Herniation NCT07386548 | Recruiting | Not applicable | United States | Weill Medical College of Cornell University | 2026-08-30 |
| Impairment Based Treatment Versus Modified Functional Restoration Program in Chronic Low Back Pain Patients NCT07699419 | Not yet recruiting | Not applicable | Egypt | Cairo University | 2026-07-01 |
| Chronic Low Back Pain Comorbidities: Unravelling Impaired Glucose Metabolism NCT07734714 | Not yet recruiting | Not applicable | Belgium | Vrije Universiteit Brussel | 2026-07 |
| Focal Extracorporeal Shock Wave Therapy With Two Different Dosing Regimens for Chronic Low Back Pain NCT07646132 | Not yet recruiting | Not applicable | Mexico | Armando Tonatiuh Avila Garcia | 2026-06-15 |
| Connective Tissue Dry Needling for Low Back Pain Related to Local Posterior Superior Iliac Spine Pain NCT07345871 | Not yet recruiting | Not applicable | | University of Social Welfare and Rehabilitation Science | 2026-04-10 |
| Chronic Low Back Pain and Osteopathic Manipulation Treatment NCT07161661 | Recruiting | Not applicable | United States | Edward Hines Jr. VA Hospital | 2026-03-02 |
| A Superiority Trial of Radiofrequency Ablation for Low Back Pain NCT07222462 | Recruiting | Not applicable | United States | University of Washington | 2026-02-04 |
| Percussive Massage Therapy Using Heat Attachment in Chronic Low Back Pain NCT07346651 | Not yet recruiting | Not applicable | Turkey (Türkiye) | Fenerbahce University | 2026-01-12 |
| Clinical Research on the Comparative Effectiveness and Safety of JHG002 Therapy for Chronic Low Back Pain: A Multicenter Randomized Controlled Trial NCT07304076 | Recruiting | Not applicable | South Korea | Jaseng Medical Foundation | 2025-12-17 |
| Resilience Enhancement Following Sleep Treatment NCT07298941 | Recruiting | Phase 2 | United States | University of Virginia | 2025-12-16 |
| How Osteopathic Treatment Affects the Leg and Foot in People With Low Back Pain NCT07193212 | Recruiting | Not applicable | United States | Edward Via Virginia College of Osteopathic Medicine | 2025-11-05 |
| Exploring Multidimensional Trajectories in People With Low Back Pain NCT07176845 | Recruiting | | Switzerland | Bern University of Applied Sciences | 2025-10-16 |
| Virtual Reality-Based Rehabilitation in Chronic Low Back Pain: Effects on Muscle Architecture, Balance, and Satisfaction (VR-LBPREHAB) NCT07172828 | Not yet recruiting | Not applicable | Turkey (Türkiye) | Hacettepe University | 2025-10-13 |
| A Prospective Evaluation of Spinal Cord Induced Muscle Stimulation (MuscleSCS) for the Treatment of Chronic Low Back Pain NCT07215104 | Recruiting | Not applicable | United States | Saint Francis Hospital | 2025-10-07 |
| Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study NCT06973837 | Recruiting | | Belgium | Vrije Universiteit Brussel | 2025-10-03 |
| Comparison of the Immediate Effect of Passive vs. Passive-Active Hamstring Stretching on Flexibility in Patients With Chronic Low Back Pain NCT06888895 | Recruiting | Not applicable | France | University Hospital, Clermont-Ferrand | 2025-09-30 |
| Predicting Pain and Disability From Voice Recordings in Low Back Pain NCT07078019 | Not yet recruiting | | | nurmuhammet tas | 2025-09-28 |
| The Effect of Attention Distraction on the Adherence to Exercise, in Chronic Low Back Pain Patients. NCT07192809 | Not yet recruiting | Not applicable | Greece | University of Thessaly | 2025-09-20 |
| Lumber Stabilization Exercise Versus Back Endurance Exercise Among Female University Students NCT07163117 | Recruiting | Not applicable | Egypt | Cairo University | 2025-09-09 |
| Art Therapy for Adults With Chronic Low Back Pain NCT07141069 | Recruiting | Not applicable | Hong Kong | The Hong Kong Polytechnic University | 2025-08-16 |
| Acute Effect of Isometric Excercise on Pain Sensitivity in Adults With Chronic Low Back Pain NCT06963658 | Recruiting | Not applicable | Saudi Arabia | Taif University | 2025-08-01 |
| Brain Network Stimulation for Chronic Low Back Pain. NCT06902233 | Recruiting | Not applicable | New Zealand | University of Otago | 2025-06-12 |
| Multimodal Imaging and Biospecimen Collection for Low Back Pain (LBPB) NCT06967363 | Not yet recruiting | | China | Peking University Third Hospital | 2025-05-15 |
| Comparison Between Lumbar Stabilization Exercises and Lumbar Manipulation on Multifidus Muscle in Chronic Low Back Pain This Study Will Investigate and Compare the Effect of Lumbar Stabilization Exercises and Manipulation on Multifidus Muscle in Chronic Low Back Pain NCT06796023 | Not yet recruiting | Not applicable | | Cairo University | 2025-01-20 |
| Cost-Effectiveness Analysis of a Virtual Reality-Assisted Hypnotherapy Program on Quality of Life in Patients with Chronic Low Back Pain: a Multicenter, Randomized, Prospective, Comparative, Open-Label, Parallel-Group Study NCT06698354 | Not yet recruiting | Not applicable | Turkey (Türkiye) | University of Beykent | 2024-12-02 |
| Traditional Medicine Use in Low Back Pain NCT06627101 | Not yet recruiting | | | Federal University of Amapa | 2024-10-26 |
| Brief Pain Exposure Therapy (BPET) For Nociplastic Pain NCT06208514 | Recruiting | Not applicable | United States | University of Michigan | 2024-03-04 |
| Movement Quality and Balance Improvement in People With Chronic Low Back Pain Following Trunk Muscle Training NCT06944730 | Recruiting | Not applicable | Hong Kong | The Hong Kong Polytechnic University | 2022-06-01 |
| Lumbar Extension Strengthening in Addition to Manual Therapy and Exercise for Chronic Low Back Pain NCT07719452 | Enrolling by invitation | Not applicable | United States | Brooke Army Medical Center | 2026-08-03 |
| Pain Neuroscience Education for Chronic Pain NCT07693998 | Enrolling by invitation | Not applicable | Spain | University of Valencia | 2026-05-05 |
| Efficacy of Electroacupuncture Combined With Auricular Acupressure for Chronic Low Back Pain. NCT07530042 | Completed | Not applicable | Vietnam | University of Medicine and Pharmacy at Ho Chi Minh City | 2026-04-20 |
| Effectiveness of ELDOA Stretching Combined With Standard Physiotherapy in Adults With Chronic Low Back Pain and Dural Hypomobility; A Randomized Controlled Trial. NCT07730463 | Completed | Not applicable | Pakistan | Ibadat International University, Islamabad | 2026-01-10 |
| Validity and Reliability of Face-to-Face and Tele-Assessment of Core Stability and Functional Capacity NCT07256873 | Completed | | Turkey (Türkiye) | Istinye University | 2025-11-30 |
| Egoscue and Core Stabilization for Chronic Low Back Pain NCT07684118 | Enrolling by invitation | Not applicable | Pakistan | University of Lahore | 2025-11-15 |
| Comparative Study on SNAG From Different Positions Low Back Pain Treatment NCT07215286 | Completed | Not applicable | Saudi Arabia | University of Hail | 2025-10-15 |
| Can Virtual Reality Exercise Help Restore Both Body and Mind in Chronic Low Back Pain NCT07207083 | Enrolling by invitation | Not applicable | South Korea | dongmin kang | 2025-09-28 |
| Pain Resilience Therapy for Low Back Pain. NCT06971809 | Completed | Not applicable | United States | Integrative Pain Science Institute | 2025-05-31 |
| A Mediation Analysis Investigating Dry Needling Treatment Mechanisms in a Chronic Low Back Pain Population NCT06940492 | Completed | Not applicable | United States | University of Florida | 2025-05-12 |
| Trunk Control Training and Walking in Older Adults NCT06782919 | Withdrawn | Not applicable | United States | Beth Israel Deaconess Medical Center | 2025-05 |
| Electrical Dry Needling Versus Sham Dry Needling in Patients With Chronic Low Back Pain NCT07148635 | Completed | Not applicable | Pakistan | University of Lahore | 2025-04-09 |
| Efficacy of Antibiotic Treatment for Patients With Chronic Low Back Pain and Modic Type I Changes - Randomized Placebo-controlled Trial NCT06771492 | Active, not recruiting | Phase 3 | Netherlands | Bart Koes | 2025-04-02 |
| Trigger Point Electroacupuncture Treatment in Patients With Chronic Low Back Pain NCT06868173 | Completed | Not applicable | Vietnam | University of Medicine and Pharmacy at Ho Chi Minh City | 2025-03-15 |