Hyperalgesia: clinical trials and information
Hyperalgesia clinical trials in Canada
| Phase | Provinces | ||||
|---|---|---|---|---|---|
| Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy NCT04902547 | Completed | Not applicable | Manitoba | University of Manitoba | 2021-05-01 |
Hyperalgesia clinical trials worldwide (outside Canada)
14 trials, 1 recruiting or not yet recruiting. Recruiting first.
| Phase | Countries | ||||
|---|---|---|---|---|---|
| Electroacupuncture Pain Treatment, Mechanical Hyperalgesia, Quality of Life & Expression of Mu+ B Cells in Fibromyalgia NCT05357157 | Recruiting | Greece | University of Crete | 2022-05-31 | |
| STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis NCT05603702 | Active, not recruiting | Phase 1 | United States | Indiana University | 2023-03-17 |
| Erector Spine Plane Block Versus Local Infiltration Anaesthesia For Transforaminal Percutaneous Endoscopic Discectomy NCT05483647 | Completed | Not applicable | Ukraine | Lviv National Medical University | 2021-01-01 |
| Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations NCT04697498 | Unknown status | Not applicable | Ukraine | Lviv National Medical University | 2020-12-16 |
| Electrophysiological Correlates of Nocebo Effects on Pain NCT04199858 | Completed | Not applicable | Netherlands | Leiden University Medical Center | 2019-10-21 |
| Pain-related Fear as a Facilitator of Nocebo Hyperalgesia NCT04197154 | Completed | Not applicable | Netherlands | Leiden University Medical Center | 2019-10-14 |
| The Role of Learning in Nocebo Hyperalgesia NCT03793790 | Completed | Not applicable | Netherlands | Leiden University Medical Center | 2018-09-20 |
| Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting NCT03450161 | Completed | Phase 4 | Belgium | University Hospital, Ghent | 2018-05-14 |
| Preventing Pain After Heart Surgery NCT01480765 | Completed | Phase 4 | United Kingdom | Barts & The London NHS Trust | 2011-12-12 |
| Local Anesthetic Infusion and Sternotomy NCT00802048 | Terminated | Phase 3 | France | University Hospital, Bordeaux | 2009-02 |
| Effect of Ketamine on Opioid-Induced Hyperalgesia NCT00833755 | Completed | Not applicable | United States | Massachusetts General Hospital | 2008-09 |
| Effects of Nefopam on Hyperalgesia After Cardiac Surgery NCT00413257 | Completed | Phase 2, Phase 3 | France | University Hospital, Bordeaux | 2006-12 |
| GW406381 In Patients With Peripheral Nerve Injury NCT00279032 | Completed | Phase 1 | United Kingdom | GlaxoSmithKline | 2003-09 |
| Positron Emission Tomography to Measure Pain and Pain Control NCT00001307 | Completed | United States | National Institute of Dental and Craniofacial Research (NIDCR) | 1992-08 |
About Hyperalgesia
What is Hyperalgesia?
"Hyperalgesia" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 15 chronic pain registry records worldwide.
How is Hyperalgesia usually assessed?
Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.
What kinds of treatments are studied for Hyperalgesia?
Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.
How can I find Hyperalgesia clinical trials in Canada?
This page lists 1 registry record for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.
Related interventions
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.