Pulsed Radiofrequency and Osteoarthritic Chronic Knee Pain
CompletedNot applicableNCT04454710
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to investigate the efficacy and safety of pulsed radiofrequency of the saphenous nerve in the treatment of pain due to knee osteoarthritis (OA). The investigators will conduct real pulsed radiofrequency or sham, over the saphenous nerve during 4 separate sessions. The investigators will evaluate pain intensity, quality of life, function, and disability via clinical validated scales. The research question is whether pulsed radiofrequency can lessen knee pain and improve function and quality of life in patients with chronic knee pain due OA. It is hypothesized, that less knee pain and improved function, and quality of life after the pulsed radiofrequency sessions.
Study details
- Official title
- The Efficacy of Pulsed Radiofrequency on the Saphenous Nerve in Osteoarthritic Chronic Knee Pain
- Conditions
- Pulsed Radiofrequency
- Osteoarthritis, Knee
- Knee Pain Chronic
- Knee Arthritis
- Interventions
- Device: Pulsed Radiofrequency
- Sponsor
- University of Rome Tor Vergata
- Start date
- 2020-01-01
- Primary completion
- 2021-02-01
- Sex
- All
- Age range
- from 18 Years to 80 Years
- Results posted
- No results posted in this snapshot
- Countries
- Italy
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Chronic knee pain (present for at least 6 months), of moderate-severe intensity (assessed by NRS =\> 6), not responsive to conservative treatments (physiotherapy, oral analgesics). * Diagnosis of knee osteoarthritis confirmed by instrumental investigation (X-ray and/or MRI) and Oxford Knee Score = \<35. * Positivity to the diagnostic block of no. saphenous (defined as a reduction of at least 50% of the NRS score). * If the patient is taking opioids or other morphine equivalents, the dosage should not be changed within 3 months prior to the study enrollment visit. Exclusion Criteria: * Body Mass index \> 40 kg /m2 * History of systemic inflammatory disease, uncontrolled diabetes mellitus, neoplastic pathology, coagulopathy * Previous knee replacement implant
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04454710