Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery
Unknown statusNot applicableNCT04718116
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The aim of this randomized one-blinded study will be to evaluate the efficacy and tolerability of two different oral doses of tapentadol and compare it to tramadol (an opioid commonly used to treat post-surgical pain) in cardiac surgery patients
Study details
- Official title
- Management of Postsurgical Pain After Cardiac Operations: Comparison of Tapentadol and Tramadol Analgesia
- Conditions
- Interventions
- Drug: Group tapentadol 50 mg
- Drug: group tapentadol 75 mg
- Drug: group tramadol 100 mg
- Sponsor
- Aretaieion University Hospital
- Start date
- 2022-11-01
- Primary completion
- 2024-12-31
- Sex
- All
- Age range
- from 18 Years to 75 Years
- Results posted
- No results posted in this snapshot
- Countries
- Greece
- Total sites listed
- 2
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * age \<75 years old * patients discharged from Intensive Care Unit (ICU) in less than 30 hours * elective cardiac surgery Exclusion Criteria: * hepatic failure (increased transaminase levels * renal failure (creatinine\> 2 mg/dL) * ileus * emergency surgery (hemorrhage, tamponade, aortic dissection) * readmission in ICU * treatment with monoaminoxidase inhibitors, selective serotonine reuptake inhibitors or antiepileptics * age\>75 years old * communication or language barriers * Lack of informed consent
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04718116