Morphine sulfate: US FDA label indications

Indications and usage (label excerpt)

1 INDICATIONS AND USAGE Morphine sulfate is an opioid analgesic indicated for the relief of moderate to severe acute and chronic pain where use of an opioid analgesic is appropriate. Morphine sulfate is an opioid analgesic indicated for the relief of moderate to severe acute and chronic pain where an opioid analgesic is appropriate. ( 1 )

Warnings (label excerpt)

5 WARNINGS AND PRECAUTIONS • Respiratory depression: Increased risk in elderly, debilitated patients, those suffering from conditions accompanied by hypoxia, hypercapnia, or upper airway obstruction. ( 5.1 ) • Controlled substance: Morphine sulfate is a Schedule II controlled substance with an abuse liability similar to other opioids. ( 5.2 ) • CNS effects: Additive CNS depressive effects when used in conjunction with alcohol, other opioids, or illicit drugs. ( 5.3 ) • Elevation of intracranial pressure: May be markedly exaggerated in the presence of head injury, other intracranial lesions. ( 5.4 ) • Hypotensive effect: Increased risk with compromised ability to maintain blood pressure. ( 5.5 ) • Prolonged gastric obstruction: In patients with gastrointestinal obstruction, especially paralytic ileus. ( 5.6 ) • Sphincter of Oddi spasm and diminished biliary/pancreatic secretions. Increased risk with biliary tract disease. ( 5.7 ) • Impaired mental/physical abilities: Caution must be use…

Excerpts are shortened. Read the full label, and ask a pharmacist or prescriber about any medicine. Full label on DailyMed(opens in a new tab) For products sold in Canada, see the Health Canada Drug Product Database(opens in a new tab).

Trials whose interventions mention this drug

Canadian trials first. Showing 50 of 62. A match on the drug name does not mean the trial studied this specific product.