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Chronic Postoperative Pain: clinical trials and information

"Chronic Postoperative Pain" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 35 chronic pain registry records worldwide.
2
Trials with Canadian sites
0
Recruiting in Canada
35
Registry records worldwide

Chronic Postoperative Pain clinical trials in Canada

2 trials, recruiting first
PhaseProvinces
Pain Control Following Total Hip Arthroplasty
NCT05062356
CompletedPhase 1QuebecSt. Mary's Research Center, Canada2021-11-04
Effects of Perioperative Pregabalin for Post-Craniotomy Pain
NCT01591980
WithdrawnPhase 4OntarioUnity Health Toronto2013-08

Chronic Postoperative Pain clinical trials worldwide (outside Canada)

33 trials, 8 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Prevention of Postsurgical Chronic Pain in Children and Adolescents (PREVENDOL)
NCT06638437
Not yet recruitingNot applicableSpainUniversity Rovira i Virgili2026-11-01
Comparison of Two Postoperative Care Strategies After Breast Surgery
NCT07880223
Not yet recruitingNot applicableGreeceMoumtzidou Maria Aikaterini2026-10
Parasternal Intercostal Nerve Block and Chronic Pain After Cardiac Surgery
NCT07818512
Not yet recruitingNot applicableBakirkoy Dr. Sadi Konuk Research and Training Hospital2026-09-28
Cardiac Surgery, the Incidence and Impact of Chronic postOperative Pain: a Survey
NCT07640646
RecruitingBelgiumUniversitaire Ziekenhuizen KU Leuven2026-06-01
Comparison of the Efficacy and Safety of Intravenous Buprenorphine Administered Via PCA System Versus Oxycodone in the Management of Postoperative Pain After Video-Assisted Thoracoscopic Surgery
NCT07434427
RecruitingPhase 4PolandMedical University of Silesia2026-03-18
Benefit on Chronic Pain of Early Screening and Management of Patients With Persistent Postoperative Pain at 3 Months
NCT07160595
Not yet recruitingNot applicableFranceFondation Hôpital Saint-Joseph2025-11
Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery
NCT07257744
RecruitingTurkey (Türkiye)Karadeniz Technical University2025-02-15
Placebo Effect In Spinal Cord Electrical Stimulation for Pain
NCT06585033
RecruitingNot applicableNetherlands, Norway, SwedenSahlgrenska University Hospital2024-11-15
Preoperative Erector Spinae Plane Block Versus Paravertebral Plane Block in Decreasing Post Mastectomy Pain Syndrome
NCT06036979
Unknown statusNot applicableEgyptNational Cancer Institute, Egypt2024-07-01
PANDORA: Paravertebral AdjuNctive DexamethasOne Palmitate Reducing Chronic Pain After Caridiac Surgery
NCT05920967
CompletedNot applicableChinaXijing Hospital2023-07-11
A Comparative Effect of Echogenic Needle for Nerve Block on Acute and Chronic Postoperative Pain
NCT06281431
Unknown statusNot applicableChinaThe Second Affiliated Hospital of Chongqing Medical University2023-06-12
Surgical Outcomes Following Neurectomy Based Upon Response to Local Anesthetic Injection in Chronic Groin Pain
NCT05386693
TerminatedUnited StatesThe Cleveland Clinic2022-04-20
The Effectiveness of Thoracal Epidural Steroid and Local Anesthetic Injection
NCT06507995
CompletedNot applicableTurkey (Türkiye)Ankara University2021-08-15
Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery
NCT04670042
WithdrawnNot applicableUnited StatesStanford University2021-06-25
Chronic Postsurgical Pediatric Pain. Evaluation Risk Factors to Develop Chronic Postsurgical Pain in Children and Adolescents Undergoing Surgery in a First Level Hospital
NCT04735211
Unknown statusSpainGuillermo Ceniza Bordallo2020-12-15
Help With Early Detection of Postoperative Neuropathic Pain Using SMS After Ambulatory Surgery
NCT04313855
CompletedNot applicableFranceFondation Hôpital Saint-Joseph2020-12-09
Postoperative Painful Chronicization After Knee Replacement Surgery : Exploratory Study of BDNF's Kinetics
NCT04604847
CompletedNot applicableFranceUniversity Hospital, Montpellier2020-12-04
Persistent Postoperative Pain After Major Emergency Abdominal Surgery
NCT04508465
Unknown statusDenmarkZealand University Hospital2020-06-04
Effect of Intraoperative Dexmedetomidine on Postoperative Pain in Elderly Patients Undergoing Major Abdominal Surgery: a Secondary Analysis Based on Prospective Data
NCT07744308
CompletedChinaChinese PLA General Hospital2020-04-01
QLB After Nephrectomy
NCT03529201
CompletedNot applicablePolandMedical University of Lublin2018-05-07
Dexmedetomidine for Prevention of Chronic Postoperative Pain
NCT03275207
Unknown statusPhase 4ChinaZhongda Hospital2018-01-01
Prevalence, Impact and Predictors of Chronic Postoperative Pain
NCT03363672
Unknown statusPeking Union Medical College Hospital2018-01-01
Monocentric Observational Study: Postoperative Pain After Cesarean Section: Incidence and Risk Factors.
NCT04280432
CompletedSpainInstituto de Investigación Hospital Universitario La Paz2017-03-01
Validation of Predictive Scale of Chronic Postsurgical Pain
NCT02991287
Unknown statusSpainParc de Salut Mar2017-02
Data Collection for Prediction of Postoperative Chronic Pain for a Software
NCT02190682
CompletedTurkey (Türkiye)Istanbul University2014-10
Postoperative Pain After Ambulatory Arthroscopic Shoulder Surgery
NCT02924519
Unknown statusUniversity of Aarhus2014-05
Femoral and Epidural Block After Total Knee Arthroplasty
NCT02115945
CompletedEarly phase 1Turkey (Türkiye)Aydin Adnan Menderes University2013-02
Menstrual Phase and Postoperative Pain
NCT02137135
CompletedEarly phase 1Turkey (Türkiye)Aydin Adnan Menderes University2012-08
Does a Multimodal no-Compression Suture Technique of the Intercostal Space Reduce Chronic Post-Thoracotomy Pain?
NCT02630849
CompletedNot applicableUniversity of Roma La Sapienza2011-10
euCPSP: European Observational Study on Chronic Post Surgical Pain,PAIN-OUT Study
NCT01467102
CompletedBelgium, France, Germany, Ireland and 7 moreEuropean Society of Anaesthesiology2011-07
Low Dose Peri-operative IV Ketamine for Chronic Post-surgery Pain Prevention
NCT01296347
CompletedPhase 4United KingdomImperial College Healthcare NHS Trust2011-04
Analgesia in Laparoscopic Cholecystectomy
NCT01388946
CompletedNot applicableGreeceUniversity of Athens2010-05
Transition From Acute to Chronic Pain After Inguinal Hernia, Hysterectomy and Thoracotomy: Analysis of Risk Factors and Association With Genetic Polymorphisms
NCT01510496
CompletedSpainFundacion IMIM2009-01

About Chronic Postoperative Pain

What is Chronic Postoperative Pain?

"Chronic Postoperative Pain" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 35 chronic pain registry records worldwide.

How is Chronic Postoperative Pain usually assessed?

Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.

What kinds of treatments are studied for Chronic Postoperative Pain?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Chronic Postoperative Pain clinical trials in Canada?

This page lists 2 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related conditions

Related interventions

Related US FDA drug labels

Labels whose indications text mentions this term. US labels, not Health Canada Product Monographs.

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.